The effect of low level laser therapy on the ridge preservation process using growth factors enriched plasma and demineralized bone matrix: A Clinical trial

The aim of this study is to find out the clinical and radiographic effect of Adding LLLT (low-power lasers therapy) to PRP (platelet rich plasma) and DBM (Demineralized bone matrix) in the process of socket preservationon the height and width of ridge and also study the histological Above-mentioned materials effect on the Value of vital bone extraction of Multi-root teeth.and Achieving to a method that could Offering In terms of quantity and quality a better bone for correct and without problem putting up implant for clinicians. In this study, Patients are chosen that refer for treatment of isolated teeth (non-muller) and these teeth were beyond repair and in terms of prognosis have been considered hopeless and also has healthy adjacent teeth and they tend to use the implant. These patients become aware in the form of Written and oral from the Study conditions and after complete the written consent and questionnaire they enter to the study. Forty socket in Patients over 18 years that at least have a Non-maintenance multi-root teeth and elected due to the study output metrics and randomly (using randomizer software: http://www.randomizer.org) divided into two groups (each 14). Initial Clinical criteria Contains Width and height of bone and Width of Keratinized gum are measured. And stents are made for Patients in order to standardize the measured variables. And a CBCT scan is taken of each patient. After tooth Extraction with minimal trauma and without pressure to the Buccal bone and with using periotome socket carefully bring out the debridement granulation tissue and two treatment Protocol Contains: in first group we use PRP and demineralized bone matrix for fill the socket and in second group we use PRP and demineralized bone matrix for fill the socket with LLLT. All of the sockets completely covered by absorbent collagen membrane and coronally advanced flap and close it by using reverse cross-mattress suture technique. Instructions are given to the patient after surgery and patients are recommended to use Chlorhexidine Gluconate 0.12% Mouthwashes twice a day for two weeks. after 10 days for Suture removal and examination Restoration Area Patients will visit again.Re-evaluate the clinical criteria will be measured Three month after process of bone repair with using stents that were - Build as a guide in 4 place : mid-buccal , mid-ligual , mid-mesial and mid-distal .and also with using trephine concurrent with implant placement preparation of histological samples from bone in that area and for check the value and rate of new bone formation , residual particle , connective tissue and vital bone are sent to the laboratory.

Gum and Tooth Research Center Of Dental College, Tabriz University Of Medical Sciences