This study was conducted to evaluate the effects of short-term ginseng supplementation on muscular damage indices, in young boxers after acute exhaustive aerobic exercise. Some of the criteria inclusion was young athletes with aged 30-18 years and without chronic diseases. Moreover, the criteria of exclusion were existence of any damage and uncontrolled intake of any supplement or drugs within the past 6 months. Therefore, in semi-experimental study twenty young boxers randomly were allocated in two placebo and Ginseng supplement groups in the spring 2015. Subjects of supplement group consumed 2gr ginseng capsules daily for one week, whiles other group consumed placebo for the same amount. After seven days of supplementation all subjects of both groups underwent in an exhaustive aerobic exercise test that performed on treadmill. Venous blood samples were collected in four phases before of starting the supplementation and in the basic state after the end supplementation period and immediately before of exercises immediately after and 24 h after exercise.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2016083010512N5
Registration date:2016-09-08, 1395/06/18
Registration timing:retrospective
Last update:
Update count:0
Registration date
2016-09-08, 1395/06/18
Registrant information
Name
Sirvan Atashak
Name of organization / entity
Islamic Azad University-Mahabad Branch
Country
Iran (Islamic Republic of)
Phone
+98 44 2244 8301
Email address
s.atashak@iau-mahabad.ac.ir
Recruitment status
Recruitment complete
Funding source
Islamic Azad University
Expected recruitment start date
2015-03-21, 1394/01/01
Expected recruitment end date
2016-03-20, 1395/01/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of short-term ginseng supplementation on muscular damage indices of young boxers after acute exhaustive aerobic exercise
Public title
Effect of short-term ginseng supplementation on oxidative stress and muscular damage of young boxers after acute exhaustive aerobic exercise
Purpose
Basic scienece
Inclusion/Exclusion criteria
Inclusion criteria: Males; young athlethes; aged 18-30years; No current chronic health problems; No consumption of any supplements or steroid anabolic drugs within the past 6 months.
Exclusion criteria: Smoking; injuries; acute diseases; and uncontrolled intake of any supplement or drugs.
Age
From 18 years old to 30 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
20
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
Placebo
Used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Clinical Research Ethics Committee of the Mahabad Islamic Azad University
Street address
Islamic Azad University, Mahabad Branch, university Street, Mahabad, Iran
City
Mahabad
Postal code
Approval date
2014-11-06, 1393/08/15
Ethics committee reference number
93/م210
Health conditions studied
1
Description of health condition studied
Oxidative stress
ICD-10 code
Z50.1
ICD-10 code description
other physical therapy
Primary outcomes
1
Description
creatine kinase concentration
Timepoint
At the beginning of the study and prior of supplementation, on the seventh day and pre exercise, immediately after exercise and 24 h post exercise
Method of measurement
The craetine kinase concentration were measured with the autoanalaizer Pars Azmoon kites and
2
Description
lactate dehydrogenase concentration
Timepoint
At the beginning of the study and prior of supplementation, on the seventh day and pre exercise, immediately after exercise and 24 h post exercise
Method of measurement
The lactate dehydrogenase concentration was measured with the autoanalaizer and Pars Azmoon kites.
Secondary outcomes
1
Description
oxidative stress indices
Timepoint
prior of supplementation, pre exercise, immediately after exercise and 24 h post exercise
Method of measurement
The total antioxidant capacity of plasma was evaluated by applying the FRAP assay. Moreover, Plasma malondialdehyde concentrations spectrophotometrically were assayed by measurement of thiobarbituric acid reactive substances assay.
Intervention groups
1
Description
The supplemented group was given two gram capsules 500 mg of ginseng four times per day, for for one week
Category
Placebo
2
Description
The placebo group was given two gram capsules 500 mg of placebo (dextrose) four times per day, for one week
Category
Placebo
Recruitment centers
1
Recruitment center
Name of recruitment center
Islamic Azad University of Mahabad
Full name of responsible person
Dr Sirvan Atashak
Street address
Islamic Azad University
City
Mahabad
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Islamic Azad University of Mahabad
Full name of responsible person
Dr. Worya Karimi
Street address
Islamic Azad University, Mahabad, West Azarbayejan
City
Mahabad
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Islamic Azad University of Mahabad
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Department of Physical Education & Sports Science, Azad University, Mahabad Branch
Full name of responsible person
Dr Sirvan Atashak
Position
Associate Professor
Other areas of specialty/work
Street address
Department of Physical Education & Sports Science, Islamic Azad University, Mahabad, West Azarbayjan
City
Mahabad
Postal code
Phone
+98 44 4244 8301
Fax
Email
S.atashak@iau-mahabad.ac.ir
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Islamic Azad University of Mahabad
Full name of responsible person
Sirvan Atashak
Position
Phd Student in Psychology
Other areas of specialty/work
Street address
West Azerbaijan-Mahabad-Islamic Azad University
City
Associate Professor of exercise physiology
Postal code
Phone
+98 44 4244 8301
Fax
Email
s.atashak@iau-mahabad.ac.ir
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Islamic Azad University of Mahabad
Full name of responsible person
Sirvan Atashak
Position
Other areas of specialty/work
Street address
Islamic Azad university, Mahabad, Iran
City
Mahabd
Postal code
Phone
+98 44 4244 8301
Fax
Email
s.atashak@iau-mahabad.ac.ir
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)