This study was conducted to evaluate the effect of 8 weeks of resistance training on new biomarkers of cardiovascular disease (Lipocalin2 (LCN2) and fatty acid binding protein (A_FABP) in obese adult males. Some of the criteria inclusion was obese adults men with aged 25-35 years and without chronic diseases. Moreover, the criteria of exclusion were existence of any damage and uncontrolled intake of any supplement or drugs. Therefore, in semi-experimental study twenty four obese adults men randomly were allocated in two training and control groups in the winter 2014. Subjects of supplement group consumed 2gr ginseng capsules daily for one week, whiles other group consumed placebo for the same amount. The progressive resistance training performed three days a week with 50-80% IRM increase intensity for eight weeks. Venous blood samples were collected at pre and after training program. Moreover, body composition indicators were measured in both stages.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2017010810512N7
Registration date:2017-01-11, 1395/10/22
Registration timing:retrospective
Last update:
Update count:0
Registration date
2017-01-11, 1395/10/22
Registrant information
Name
Sirvan Atashak
Name of organization / entity
Islamic Azad University-Mahabad Branch
Country
Iran (Islamic Republic of)
Phone
+98 44 2244 8301
Email address
s.atashak@iau-mahabad.ac.ir
Recruitment status
Recruitment complete
Funding source
Islamic Azad University of Mahabad
Expected recruitment start date
2014-12-22, 1393/10/01
Expected recruitment end date
2015-12-21, 1394/09/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of 8 weeks of resistance training on new biomarkers of cardiovascular disease in obese adult males
Public title
The effect of resistance training on biomarkers of cardiovascular disease in obese adult males
Purpose
Other
Inclusion/Exclusion criteria
Inclusion criteria: Males; young athlethes; aged 25-35years; body mass index (BMI) equal or greater to 30; No current chronic health problems. Exclusion criteria: Smoking and alcol;and uncontrolled intake of any supplement or drugs.
Age
From 25 years old to 35 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
24
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Clinical Research Ethics Committee of the Mahabad Islamic Azad University
Street address
Islamic Azad University, Mahabad Branch, university Street, Mahabad, Iran
City
Mahabad
Postal code
Approval date
2014-12-06, 1393/09/15
Ethics committee reference number
93/س915
Health conditions studied
1
Description of health condition studied
cardiovascular disease risk factors
ICD-10 code
Z50.1
ICD-10 code description
other physical therapy
Primary outcomes
1
Description
Lipocalin2 (LCN2) concentration
Timepoint
At the beginning of the study and prior of training and after training program
Method of measurement
The Lipocalin2 biomarker concentration was measured with the autoanalaizer and Biovendor kites.
2
Description
fatty acid binding protein (A_FABP)
Timepoint
At the beginning of the study and prior of training and after training program
Method of measurement
The atty acid binding protein biomarker concentration was measured with the autoanalaizer and Biovendor kites.
Secondary outcomes
1
Description
body composition indices
Timepoint
At the beginning of the study and prior of training and after training program
Method of measurement
The Waist to hip ratio (WHR) was calculated as waist circumference divided by that of the hip and Fat density (fat mass) was predicted from the skin-fold measurements taken using a caliper at the triceps, abdominal, and super iliac sites.
Intervention groups
1
Description
In the training group participants were performed progressive resistance training three days a week with 50-80% IRM for eight weeks.
Category
Lifestyle
2
Description
In the control group, participants were advised to maintain their normal lifestyle during the study
Category
Lifestyle
Recruitment centers
1
Recruitment center
Name of recruitment center
Islamic Azad University of Mahabad
Full name of responsible person
Dr Sirvan Atashak
Street address
City
Mahabad
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Islamic Azad University of Mahabad
Full name of responsible person
Dr. Worya Karimi
Street address
Islamic Azad University, Mahabad, West Azarbayejan
City
Mahabad
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Islamic Azad University of Mahabad
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Department of Physical Education & Sports Science, Azad University, Mahabad Branch
Full name of responsible person
Dr Sirvan Atashak
Position
Associate Professor
Other areas of specialty/work
Street address
Department of Physical Education & Sports Science, Islamic Azad University, Mahabad, West Azarbayjan