INTRODUCTION: The bone marrow aspiration and biopsy (BMA/BMB) has a well-known role in diagnosing and staging of malignancies, evaluating platelet, white or red blood cell disorders, and defining various infectious diseases. It’s a painful procedure. Usually it’s been executed by local anesthesia (LA). Some of the clinicians use benzodiazepine in addition to local anesthesia. In spite of using local anesthesia and benzodiazepine, it’s still a painful procedure. Acupuncture and its subtypes, like transcutaneous acupoint electrical stimulation (TAES), has been proved to have analgesic effect in some pains as well as in some other painful procedures. Considering the important role of BMA/BMB in diagnosis and staging of a broad spectrum of diseases, its painfulness and its need for an easy safe and fast acting pain relieving technique, and in regard to the important role of acupuncture in relieving various pains, we want to compare the pain score in the patients undergoing BMA/BMB who receive bilateral TAES in addition to LA with the ones who don’t receive TAES. METHOD: It’s a triple blind randomized clinical trial. The patients over 18 years old requiring BMA/BMB in Sayyedoshohada Hospital enter the study. They will randomly be divided into 2 groups. Each group will consist of 25 patients. Both groups will receive local anesthesia with Lidocaine. The case group will also receive TAES on LI 4 and LI 11 bilaterally, and the control group will receive placebo TAES, then both groups will determine their pain level during BMA/BMB through VAS. The mean of VAS of each group will be compared. Before executing the procedure and once during the procedure, each patient’s blood pressure and pulse rate will be measured.