This study examined the effects of resistance and endurance training on serum leptin and adiponectin levels and insulin resistance index in sedentary postmenopausal obese women.For this porpuse; 24 sedentary menopausal obese (BMI≥30.53 Kg/m2) women (mean aged 52.25±3 years old) randomly assigned to endurance and resistance training and control groups, studied before and after 10 weeks of resistance (40-60% of one-repetition maximum) and swimming endurance training (40-60% of maximal heart rate), 3 days per week. Leptin and adiponectin levels, HOMA-IR and anthropometric measurements were assessed before and after training.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2012090210709N1
Registration date:2013-06-28, 1392/04/07
Registration timing:retrospective
Last update:
Update count:0
Registration date
2013-06-28, 1392/04/07
Registrant information
Name
Najmeh Rezaeian
Name of organization / entity
Islamic Azad University, Bojnourd branch
Country
Iran (Islamic Republic of)
Phone
+98 58 3292 2853
Email address
n.rezaeian@ut.ac.ir
Recruitment status
Recruitment complete
Funding source
investigator
Expected recruitment start date
2008-06-21, 1387/04/01
Expected recruitment end date
2009-01-20, 1387/11/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Hormonal Adaptations to Endurance Training Versus Resistance in Postmenopausal Obese Women
Public title
exercise training and adipokines
Purpose
Health service research
Inclusion/Exclusion criteria
Inclusion criteria: 45-60 years old women; postmenopausal; obese (BMI>30 kg/m2); healthy (without no history of diabetes, cardiovascular and neurological diseases); sedentary
Exclusion criteria: women younger than 45 and older than 60; non- menopausal; not obese; with disease effecting on process and result of study; athletes
Age
From 45 years old to 60 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
24
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Alzahra University
Street address
Alzahra University, Deh Vanak, Tehran
City
Tehran
Postal code
-
Approval date
2009-06-15, 1388/03/25
Ethics committee reference number
25/3/88 / 456 / ت د
Health conditions studied
1
Description of health condition studied
Insulin resistance
ICD-10 code
E10, E11,
ICD-10 code description
Diabetes mellitus, Obesity and other hyperalimentation
Primary outcomes
1
Description
leptin
Timepoint
befor and after 48 hours after
Method of measurement
elisa
2
Description
adiponectin
Timepoint
before and 48 hours after training
Method of measurement
elisa
Secondary outcomes
1
Description
insulin resistance index (HOMA-IR)
Timepoint
before and 48 hours after training
Method of measurement
Fasting serum glucose concentrations were measured by glucose oxidase method using a Beckman Glucose Analyzer (Beckman Instruments, Irvine, CA). Insulin was measured by radioimmunoassay with commercial kits (Immuno Nucleo, Stillwater, MN). The homeostasis model assessment of insulin resistance (HOMA-IR) was calculated using the HOMA-IR equation: [fasting insulin (μU/mL) × fasting glucose (mmol/L)/ 18]/ 22.5
Intervention groups
1
Description
The endurance training group: Subjects participated in 10 weeks of endurance swimming training/ walking in water (pool) at an intensity corresponding to 40-60% of maximal heart rate, 3 days per week.
Category
Lifestyle
2
Description
control group: without Intervention
Category
Lifestyle
3
Description
The resistance training group: subjects participated in 10 weeks of resistance training, 3 days per week, including: three sets (with 60-90 second rest intervals) of 10 to 12 repetitions, at an intensity corresponding to 40- 60% of one-repetition maximum.
Category
Lifestyle
Recruitment centers
1
Recruitment center
Name of recruitment center
Tavanir sports complex
Full name of responsible person
Street address
City
Tehran
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Vice Chancellor for Research of Alzahra University
Full name of responsible person
Dr Ensieh Zahedi
Street address
Alzahra University, Dehvanak, Tehran
City
Tehran
Grant name
-
Grant code / Reference number
-
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice Chancellor for Research of Alzahra University
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Department of Sports and Exercise Physiology, Faculty of Sports and Exercise Sciences, University of
Full name of responsible person
Najme Rezaeian
Position
Ph.D Student
Other areas of specialty/work
Street address
Faculty of Sports and Exercise Sciences, University of Tehran, North Amirabad, Tehran
City
Tehran
Postal code
Phone
+98 21 8209 5954
Fax
Email
Rezaeian.n@gmail.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Alzahra University
Full name of responsible person
Hamide Montazery Taleghani
Position
MSc
Other areas of specialty/work
Street address
Alzahra University, Dehvanak, Tehran
City
Tehran
Postal code
-
Phone
+98 21 8899 0830
Fax
Email
Hamideh.montazery@yahoo.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Department of Sports and Exercise Physiology, Faculty of Sports and Exercise Sciences, University of
Full name of responsible person
Najme Rezaeian
Position
Ph.D Student
Other areas of specialty/work
Street address
Faculty of Sports and Exercise Sciences, University of Tehran, North Amirabad, Tehran
City
Tehran
Postal code
Phone
+98 21 8209 5954
Fax
Email
Rezaeian.n@gmail.com
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)