Objective: Adipolin is a novel anti-inflammatory adipokine with insulin-sensitizing effects that ameliorates glucose intolerance and insulin resistance. . This study investigated effect of intensity of aerobic training on adipolin and furin levels and insulin resistance index in sedentary overweight men.
Design: 36 sedentary؛ overweight men (BMI>25 Kg/m2)؛ obesity and overweight not related to hypothyroidism؛ healthy men؛ without kidney disease diabetes؛ no physical
problems &injury؛ no physical activity during three years ago ؛ assigned randomly.
in three training groups of low and high intensity and control groups.
People who had not above conditions exclusion from study.
Low intensity training group run at intensity of 50-70 % of maximal heart rate .high intensity training group run at 70-90% of maximal heart rate at 30-45 minutes per session and three sessions per week for 10 weeks and Control group were without intervention. Levels of adipolin, furin, insulin and fasting glucose and anthropometric indices measured before and 72 hours after last training session.
Adipolin and furin were primary outcome measure and insulin resistance index was secondary outcome measure.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2016010310709N3
Registration date:2016-01-16, 1394/10/26
Registration timing:retrospective
Last update:
Update count:0
Registration date
2016-01-16, 1394/10/26
Registrant information
Name
Najmeh Rezaeian
Name of organization / entity
Islamic Azad University, Bojnourd branch
Country
Iran (Islamic Republic of)
Phone
+98 58 3292 2853
Email address
n.rezaeian@ut.ac.ir
Recruitment status
Recruitment complete
Funding source
Private
Expected recruitment start date
2014-04-21, 1393/02/01
Expected recruitment end date
2014-07-06, 1393/04/15
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Evaluation of the impact of training intensity in the plasma levels of adipolin and furin in obese middle age men
Public title
Effect of aerobic training on adipolin & furin
Purpose
Health service research
Inclusion/Exclusion criteria
Inclusion criteria:Middle age men؛ sedentary ؛ overweight( (BMI>25 Kg/m2)؛ obesity and overweight not related to hypothyroidism؛ healthy men؛ without kidney disease diabetes؛ no physical
problems &injury؛ no physical activity during three years ago ؛ assigned randomly.
Exclusion criteria: People who had not above conditions.
Age
From 35 years old to 50 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
36
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics of Zahedan Medical Science University
Street address
Zahedan Medical Science University، Daneshghah street