Comparison of outcomes and complications of vaginal misoprostol Preoperative administration of oxytousin infusion during surgery to reduce bleeding during abdominal myomectomy

The aim of the study was to reduce bleeding during myomectomy via laparotomy in patients with uterine myoma is due to include women with uterine myoma laparotomy candidates and Interested to participate in the study and no Allergies for misoprostol or oxytocin and No consumption hormonal therapy Before surgery, no active liver or heart or renal or Pulmonary disorders or hypertention and Coagulopathy. 105 female candidates for abdominal myomectomy referred to Zahra Hospital Medical Center are selected . infusion oxytocin 30 unit into 1000 ml normal saline speed of 120 ml/hour before starting anesthesia to Removing the compelete uterine from pelvic ( 35 patients) and misoprostol single dose of 400 mcg vaginally one hour before surgery during the operation the size of the oxytocin group received normal saline, recommends that ( 35 cases ) treated by routine non adminestration drug before and during surgery during the same volume of saline recommends that oxytocin group ( 35 cases ) on bleeding during myomectomy patients will be compared . For each of the study groups during the monitoring routine hemodynamic variables , primary outcome of reducing bleeding as bleeding ( the blood in suction and blood is absorbed in sponges to long Gas 50 cc and gas 5 ml ) It is estimated and Subsequent outcome hemoglobin before and after the surgery and the need for blood transfusion and durtion of hospitalization and durtion of surgery as measured by the three groups will be compared .

Women's Reproductive Health Research Center, Tabriz University of Medical Sciences