Protocol summary

Summary
The aim of this study is to compare the acute effects of endurance exercise (EE), resistance exercise (RE), and concurrent exercise (CE) on immune and hormone changes in active men. One hundred thirty healthy young men (no history of special diseases, nonalcoholic and nonsmokers) as a research population, will perform two months regular physical activity (at least 2 days a week). So, as a active men, twenty one subject voluntarily will participate as a sample of this study and randomly will assign into three groups: endurance exercise (EE) (n=7), resistance exercise (RE) (n=7), and concurrent exercise (CE) (n=7). Four days before exercise session, anthropometric and body composition factors will measure and one-repetition maximum of RE and CE groups will calculate with Brzycki formula. Subjects will prohibit from any exercise activity three days before exercise session and will fast at least 12 hours before first sampling until last sampling (not eat any food). Special exercise protocol will perform consisted of 45 min for each group. Blood samples (4 cc) will obtain from antecubital vein before exercises, immediate and 1 hour post-exercises and will pour into free EDTA tubes. Fasting Blood Suger will determine by the enzymatic method and IL-17, IL-10, cortisol and testosterone will measure by ELISA method.

General information

Acronym
IRCT registration information
IRCT registration number: IRCT2012100511011N1
Registration date: 2014-08-02, 1393/05/11
Registration timing: retrospective

Last update:
Update count: 0
Registration date
2014-08-02, 1393/05/11
Registrant information
Name
Mostafa Baranchi
Name of organization / entity
Tarbiat Modares University
Country
Iran (Islamic Republic of)
Phone
+98 21 6659 1514
Email address
m.baranchi@modares.ac.ir
Recruitment status
Recruitment complete
Funding source
Tarbiat Modares University
Expected recruitment start date
2013-08-23, 1392/06/01
Expected recruitment end date
2014-06-22, 1393/04/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of Immune and Hormone Changes in Response to Endurance, Resistance and Concurrent Exercise
Public title
Comparison of Immune and Hormone Changes in Response to Endurance, Resistance and Concurrent Exercise
Purpose
Health service research
Inclusion/Exclusion criteria
Inclusion criteria: Healthy young men (No history of special diseases, Nonalcoholic and Nonsmokers); At least two months regular physical activity, at least 2 days a week; Normal BMI and body fat percentage; Not consuming special drugs or any other nutritional supplements Exclusion criteria: Less than 2 month exercise training period
Age
From 18 years old to 25 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 130
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Tarbiat Modares University
Street address
Department of Physical Education and Sports Sciences, Faculty of Humanities, Tarbiat Modares University, Jalal Ale Ahmad Highway, Tehran, Iran. P.O.Box: 14115-111.
City
Tehran
Postal code
14115-111
Approval date
2014-07-12, 1393/04/21
Ethics committee reference number
52/3063د

Health conditions studied

1

Description of health condition studied
Lifestyle-related condition
ICD-10 code
Y98
ICD-10 code description
Lifestyle-related condition

Primary outcomes

1

Description
interleukin-17
Timepoint
Pre, immediate and 1 h post-exercises
Method of measurement
ELISA

2

Description
interleukin-10
Timepoint
Pre, immediate and 1 h post-exercises
Method of measurement
ELISA

3

Description
Testosterone
Timepoint
Pre, immediate and 1 h post-exercises
Method of measurement
ELISA

4

Description
Cortisol
Timepoint
Pre, immediate and 1 h post-exercises
Method of measurement
ELISA

Secondary outcomes

1

Description
Fasting blood suger
Timepoint
Pre, immediate and 1 h post-exercises
Method of measurement
Enzymatic

2

Description
Body fat percentage
Timepoint
Pre session
Method of measurement
Bioelectrical impedance

Intervention groups

1

Description
Endurance exercise
Category
Lifestyle

2

Description
Resistance exercise
Category
Lifestyle

3

Description
Concurrent exercise
Category
Lifestyle

Recruitment centers

1

Recruitment center
Name of recruitment center
Payame Noor University of Hamedan
Full name of responsible person
Mostafa Baranchi
Street address
City
Hamedan

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Tarbiat Modares University
Full name of responsible person
Dr. Hamid Agha-alinejad
Street address
Department of Physical Education and Sports Sciences, Faculty of Humanities, Tarbiat Modares University, Jalal Ale Ahmad Highway, Tehran, Iran.
City
Tehran
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Tarbiat Modares University
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Tarbiat Modares University
Full name of responsible person
Mostafa Baranchi
Position
MSc
Other areas of specialty/work
Street address
Enghelab square, Azadi street cross Jamalzadeh, Shahid Khaleghi Allay, Heidari Dormitory, unit8, Tehran, Iran.
City
Tehran
Postal code
1418914961
Phone
+98 21 6690 7632
Fax
Email
m.baranchi@modares.ac.ir
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Tarbiat Modares University
Full name of responsible person
Mostafa Baranchi
Position
MSc
Other areas of specialty/work
Street address
Department of Physical Education and Sports Sciences, Faculty of Humanities, Tarbiat Modares University, Jalal Ale Ahmad Highway, Tehran, Iran.
City
Tehran
Postal code
Phone
+98 21 6690 7632
Fax
Email
m.baranchi@modares.ac.ir
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Tarbiat Modares University
Full name of responsible person
Mostafa Baranchi
Position
MSc
Other areas of specialty/work
Street address
Enghelab square, Azadi street cross Jamalzadeh, Shahid Khaleghi Allay, Heidari Dormitory, unit8, Tehran, Iran.
City
Tehran
Postal code
6515974469
Phone
+98 21 6690 7632
Fax
Email
m.baranchi[a]modares[dot]ac[dot]ir
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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