Effect of Eight Weeks of Aerobic Training on Some Factors of vessel Endothelial Function and Changes of Estrogen Hormone in non-active Postmenopausal Women
The aim of this study is to investigate the effects of eight weeks of aerobic training on some factors of vessel endothelial function and changes of estrogen hormone in non-active postmenopausal women. Methodology: 20 volunteer of postmenopausal women randomly assigned to experimental and control groups. Subjects don’t exercise regularly and if there is any type of physical injury, and orthopedic exercises to interfere with the implementation of the survey, subjects will be excluded. Experimental group exercise (eight weeks with a frequency of three sessions per week of walking for 30 to 45 minutes per session) with 50 to 70 percent of heart rate reserve. Before and after the exercise program, weight, percent body fat, FMD, ACE, nitric oxide, estrogen hormone will be measured.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2012102411250N1
Registration date:2012-11-30, 1391/09/10
Registration timing:retrospective
Last update:
Update count:0
Registration date
2012-11-30, 1391/09/10
Registrant information
Name
Samaneh Farahati
Name of organization / entity
Ferdowsi university of Mashhad
Country
Iran (Islamic Republic of)
Phone
+98 51 1868 3090
Email address
sa_fa316@stu-mail.um.ac.ir
Recruitment status
Recruitment complete
Funding source
Ferdowsi university of Mashhad
Expected recruitment start date
2012-04-08, 1391/01/20
Expected recruitment end date
2012-06-18, 1391/03/29
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of Eight Weeks of Aerobic Training on Some Factors of vessel Endothelial Function and Changes of Estrogen Hormone in non-active Postmenopausal Women
Public title
Effect of Eight Weeks of Aerobic Training on Some Factors of vessel Function
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria: At least one year past from the menopause. Menopause is occur naturally; without regular physical activity. Exclusion criteria: Any physical injury and orthopedic to interfere with training and Hinder the quality of training.
Age
From 45 years old to 60 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
20
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Department of Physical Education and Sports Sciences, Ferdowsi University of Mashhad
Street address
Ferdowsi university of Mashhad
City
Mashhad
Postal code
Approval date
2012-05-28, 1391/03/08
Ethics committee reference number
23039
Health conditions studied
1
Description of health condition studied
postmenopausal
ICD-10 code
N95.1
ICD-10 code description
Menopausal and female climacteric states
Primary outcomes
1
Description
Flow mediated dilation
Timepoint
before training-after training
Method of measurement
Doppler Ultrasonography
2
Description
Angiotensin-converting enzyme
Timepoint
before training-after training
Method of measurement
HPLC method
3
Description
nitric oxide
Timepoint
before training-after training
Method of measurement
ELISA kit
4
Description
estrogen hormone
Timepoint
before training-after training
Method of measurement
Electroluminance
Secondary outcomes
empty
Intervention groups
1
Description
Experimental group exercise (eight weeks with a frequency of three sessions per week of walking for 30 to 45 minutes per session) with 50 to 70 percent of heart rate reserve
Category
Other
2
Description
Control groups were without training over eight weeks
Category
N/A
Recruitment centers
1
Recruitment center
Name of recruitment center
Ferdowsi university of Mashhad
Full name of responsible person
Street address
City
Mashhad
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Department of Physical Education and Sports Sciences, Ferdowsi University of Mashhad
Full name of responsible person
Seyyed Reza Attarzadeh Hosseini
Street address
Ferdowsi University of Mashhad
City
Mashhad
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Department of Physical Education and Sports Sciences, Ferdowsi University of Mashhad
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Department of Physical Education and Sports Sciences, Ferdowsi University of Mashhad
Full name of responsible person
Seyyed Reza Attarzadeh Hosseini
Position
Associate Professor in Sport Physiology Faculty of Physical Education and Sport Sciences
Other areas of specialty/work
Street address
Ferdowsi University of Mashhad
City
Mashhad
Postal code
Phone
+98 51 1883 3910
Fax
Email
attarzadeh@um.ac.ir
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Department of Physical Education and Sports Sciences, Ferdowsi University of Mashhad
Full name of responsible person
Samaneh Farahati
Position
Msc
Other areas of specialty/work
Street address
Ferdowsi University of Mashhad, Vakil-Abad blvd.
City
Mashhad
Postal code
Phone
+98 51 1883 3910
Fax
Email
samanehfarahati@yahoo.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Full name of responsible person
Samaneh Farahati
Position
Other areas of specialty/work
Street address
City
Postal code
Phone
Fax
Email
samanehfarahati@yahoo.com
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)