Thus the goal of this research is to study the response of Leptin Plasma, 17-beta estradiol serum and insulin to 24-weeks aerobic exercise in inactive obese women. 15 inactive obese women were chosen randomly and were categorized in two different groups; i.e. aerobic exercise and control. The exercise process included aerobic exercises for 6 months (three 60-minute sessions per week).BMI, fat percentage,Leptin, 17-beta estradiol serum and insulin levels measured before and after the 24 weeks of training period.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2012122611528N3
Registration date:2013-01-21, 1391/11/02
Registration timing:retrospective
Last update:
Update count:0
Registration date
2013-01-21, 1391/11/02
Registrant information
Name
Samira Gholamian
Name of organization / entity
Ferdowsi University of Mashhad
Country
Iran (Islamic Republic of)
Phone
+98 938 642 2953
Email address
sa.gholamian1385@gmail.com
Recruitment status
Recruitment complete
Funding source
Vice chancellor for research, Ferdowsi University of Mashhad
Expected recruitment start date
2012-04-13, 1391/01/25
Expected recruitment end date
2012-06-14, 1391/03/25
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The Response of Leptin Plasma, 17-Beta Estradiol Serum and Insulin to 24-weeks Aerobic Exercise in Inactive obese Women
Public title
Effect of regular aerobic exercise on hormones
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria: Healthy; No drug based on the Health questionnaire; Non-menopausal; No participating in any exercise program. Exclusion criteria: Presence of any illness; menopause; drug consumption; smoking; participating in any exercise program
Age
From 37 years old to 47 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
15
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Vice chancellor for research, Ferdowsi University
Street address
Ferdowsi University of Mashhad, Azadi Square, Mashhad
City
Mashhad
Postal code
Approval date
2012-04-08, 1391/01/20
Ethics committee reference number
215
Health conditions studied
1
Description of health condition studied
obesity
ICD-10 code
E66
ICD-10 code description
obesity
Primary outcomes
1
Description
Leptin
Timepoint
48 hours before exercise program and 48 hours after the last session after 6 months exercise
Method of measurement
48 hours before exercise program and 48 hours after the last session after 6 months exercise
2
Description
17-beta estradiol
Timepoint
48 hours before exercise program and 48 hours after the last session after 6 months exercise
Method of measurement
48 hours before exercise program and 48 hours after the last session after 6 months exercise
3
Description
Insulin
Timepoint
48 hours before exercise program and 48 hours after the last session after 6 months exercise
Method of measurement
48 hours before exercise program and 48 hours after the last session after 6 months exercise
Secondary outcomes
1
Description
body mass index
Timepoint
48 hours before exercise program and 48 hours after the last session after 6 months exercise
Method of measurement
weight/ (hight)*(hight)
2
Description
fat percent
Timepoint
48 hours before exercise program and 48 hours after the last session after 6 months exercise
Method of measurement
caliper
Intervention groups
1
Description
The exercise protocol included aerobic (endurance) exercise training lasted to 6 months and 3 sessions per week and every session lasted to 60 minutes and with intensity of 55-65 percent of heart rate reserve
Category
Other
2
Description
control:Lack of exercise participation
Category
Diagnosis
Recruitment centers
1
Recruitment center
Name of recruitment center
Ferdowsi University of Mashhad
Full name of responsible person
Mahtab Moazemi
Street address
City
Mashhad
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Vice chancellor for research, Ferdowsi university of Mashhad
Full name of responsible person
Mahtab Moazemi
Street address
Faculty of Physical Education and Sport Sciences, Ferdowsi university, Azadi square, Mashhad
City
Mashhad
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice chancellor for research, Ferdowsi university of Mashhad
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Ferdowsi University of Mashhad
Full name of responsible person
Mahtab Moazami
Position
Assistant professor
Other areas of specialty/work
Street address
Faculty of Physical Education and Sport Sciences, Ferdowsi university, Azadi Square, Mashhad
City
Mashhad
Postal code
Phone
+98 51 1879 7023
Fax
Email
mahtab.moazami@gmail.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Ferdowsi University of Mashhad
Full name of responsible person
Samira Gholamian
Position
M.S student
Other areas of specialty/work
Street address
Faculty of Physical Education and Sport Sciences, Ferdowsi University, Azadi square, Mashhad
City
Mashhad
Postal code
Phone
+98 51 1501 4248
Fax
Email
sa.gholamian1385@gmail.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Physical Education Faculty, Ferdowsi University of Mashhad
Full name of responsible person
Samira Gholamian
Position
Master of physical education
Other areas of specialty/work
Street address
City
Postal code
Phone
00
Fax
Email
sa.gholamian1385@gmail.com
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)