This study is a randomized clinical trial on 150 pregnant women had referred to Shoushtari hospital, Shiraz, Iran, and compares the effect of doula supportive care and acupressure on the intensity of fetal hypoxia and frequency of nucleated red blood cells in the cord blood. After obtaining informed consent, the eligible women were allocated randomly into three groups (two experimental groups and one control group). Spielberger's test was used to measure anxiety in the three groups. In the first group, the researcher as the doula was beside the mother from her entrance into the department. She reassured the mother, encouraged her, and gave her correct and appropriate information which led to the mother's tranquility, understanding the origin of pain, developing a positive attitude toward the pain experience, and increase in their cooperation in the delivery progress. In the second group, in 3-4 and 7-8cm dilatation, the mother was placed in a proper position and BL32 point was pressed. The pressure was continuously and gently applied by both thumbs for 20 minutes. It was applied by the beginning and stopped at the end of the contractions. On the other hand, the control group only received the department's routine care. The blood from the umbilical cord sent to laboratory and results record.