This study is a double-blind, parallel clinical trial on 70 patients 35 to 70 years of age taking dietary advice and medicine that reduce blood sugar .patient that 3-5 years old with diabetic nephropathy type II. HbA1c of 7-9%, LDL cholesterol and triglycerides less than 300 and less than 130 and with 0 and 1 grades of nephropathy. Patients with liver disease and end stage of nephropathy excluded. At baseline insulin levels, fasting blood glucose, HbA1C, triglycerides, total cholesterol, LDL- cholesterol, HDL- cholesterol, TAC, ALT and, BUN, creatinin, pro ,AST ,24 recall receiving food will be recorded for subjects. In addition to their previous therapy, subjects will receive 60 placebo capsules or capsule containing blueberry extract for a month prepared by Barij Essence company. Volunteers will be visited monthly and if there is no problem they will receive it again for a months. At the end of 3 months testing and initial evaluation will be repeated and changes will be investigated.