The purpose of this study is to compare the effect of 12 week aerobic and resistance training on the levels of Interleukin-18 and C - reactive protein in elderly men. For this, 30 old men were chosen after medical screening. Subjects were purposely chosen and randomly divide to 3 groups as aerobic exercise (n=10), resistance exercise (n=10) and control (n=10). Then the first blood sample was taken and height, weight and BMI were measured and calculated. Exercise groups implemented the exercise programs for 12 weeks and three non-consecutive sessions per week (aerobic groups exercised on treadmill in 50-70% of the reserve heart rate, resistance exercise were implemented in 40-70% severity with one maximum repetition). 24 hours after the last training session all variables were measured as pre -test. For comparing pre and post –test data, t-test independent and for comparing the groups, one way anova test and tukey test were used.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2013031612827N1
Registration date:2013-11-07, 1392/08/16
Registration timing:retrospective
Last update:
Update count:0
Registration date
2013-11-07, 1392/08/16
Registrant information
Name
Bijan Kabir
Name of organization / entity
Islamic Azad University, Khorasgan
Country
Iran (Islamic Republic of)
Phone
+98 38 1334 1719
Email address
bigan.rad@gmail.com
Recruitment status
Recruitment complete
Funding source
Investigator
Expected recruitment start date
2012-04-15, 1391/01/27
Expected recruitment end date
2012-07-24, 1391/05/03
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of aerobic and resistance training on interleukin-18 and c- reactive protein in elderly men
Public title
Comparison of aerobic and resistance training on interleukin-18 and c- reactive protein in elderly men
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria: male, 65 to 80 years, without experience of regular physical activity in one year before beginning of the study.
Exclusion criteria: history of cardiovascular diseases, cancer, high blood pressure, diabetes, thyroid disease, addiction to any smoking, alcohol and narcotic substances.
Age
From 65 years old to 80 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
30
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Aerobic training was performed on a treadmill. Resistance exercise with gym apparatus was performed.
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics committee Isfahan University of Medical sciences
Street address
Bldg.4, Isfahan University of Medical sciences
City
Isfahan
Postal code
81745-319
Approval date
2013-09-01, 1392/06/10
Ethics committee reference number
184/م/12/4/پ
Health conditions studied
1
Description of health condition studied
Elderly
ICD-10 code
R54
ICD-10 code description
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Primary outcomes
1
Description
Interleukin-18
Timepoint
Before and after 12 weeks of intervention
Method of measurement
ELISA kit for Interleukin-18
2
Description
Body Mass Index
Timepoint
Before and after 12 weeks of intervention
Method of measurement
Weight divided by height squared
3
Description
Weight
Timepoint
Before and after 12 weeks of intervention
Method of measurement
Weight meter Seca
4
Description
C-reactive protein
Timepoint
Before and after 12 weeks of intervention
Method of measurement
Nephlometric method
Secondary outcomes
empty
Intervention groups
1
Description
Intervention 1: The intervention group followed an aerobic exercise program for 12 weeks. This program includes warm up with stretching and then walking on a treadmill speed is increased. This one hour 3 times a week Was. In the final 10 minutes of exercise treadmill speed was gradually reduced cooling time.
Category
Other
2
Description
Intervention 3: Daily life no regular physical activity in the control group
Category
Other
3
Description
Intervention 2: The intervention group followed an resistance exercise program for 12 weeks. Resistance training protocol consisted of 3 sessions per week, 9 stations, 3 sets 8-12 repetitions in each station, intensity 40-70% of one repetition maximum, rest between sets 1 min and between stations 2 min, duration of main training 50 min per each session.
Category
Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Jahandidegan Society of Shahrekord
Full name of responsible person
Mrs. Amiri
Street address
Alley 13, Mellat ST
City
Shahrekord
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Islamic Azad University, Khorasgan (Isfahan)
Full name of responsible person
Farzaneh Taghian
Street address
Daneshgah Blvd, Arghavanieh St., East Jay St.,
City
Isfahan
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Islamic Azad University, Khorasgan (Isfahan)
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Shahrekord University of Medical Sciences
Full name of responsible person
Keihan Ghatre Samani (PhD)
Position
PhD Clinical Biochemistry, Research Assistant Shahrekord University of Medical Sciences
Other areas of specialty/work
Street address
Rahmatiyeh, University of Medical Sciences
City
Shahrekord
Postal code
Phone
+98 38 1334 6721
Fax
Email
kgsamani@yahoo.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Islamic Azad University, Khorasgan(Isfahan)
Full name of responsible person
Farzaneh Taghian
Position
Assistant Professor of Exercise Physiology
Other areas of specialty/work
Street address
Blvd Daneshgah, Arghavanieh ST, East J ST
City
Isfahan
Postal code
Phone
+98 31153540019
Fax
+98 31 1535 4060
Email
f_taghian@yahoo.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Islamic Azad University, Khorasgan(Isfahan)
Full name of responsible person
Bijan Kabir
Position
MSc of Exercise Physiology
Other areas of specialty/work
Street address
Blvd Daneshgah, Arghavanieh ST, East J ST
City
Isfahan
Postal code
Phone
+98 31153540019
Fax
+98 31153544060
Email
bigan.rad@gmail.com
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)