Comparison effect of omega-3 supplementation on postpartum depression and serum homocysteine of lactating women and growth and development of their infants
The aim of this study is to test the effect of maternal supplementation of omega-3 fatty acids during first six month of lactation on postpartum depression and serum homocysteine levels of mothers and growth and development of their infants. This study is a double-blind placebo-controlled randomized trials. The inclusion criteria are lactating women who have moderate depression and term birth. The exclusion criteria are lactating women who have severe depression and preterm birth. The sample size consist of 70 lactating women that randomly divided into two groups of 35 women: the treatment group and control group. The intervention consist of maternal supplementation containing 1 gram gel capsules of omega-3 fatty acids daily for 3 months. The control group receive gel capsules of paraffin oil as placebo daily for 3 months. The maternal outcomes of serum homocysteine and postpartum depression will be evaluated before and after the intervention. The outcomes of growth and development of the infants will be evaluated before and after the intervention as well.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2015100313678N6
Registration date:2016-03-01, 1394/12/11
Registration timing:retrospective
Last update:
Update count:0
Registration date
2016-03-01, 1394/12/11
Registrant information
Name
Saeed Ghavamzadeh
Name of organization / entity
Urmia University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 44 1278 0803
Email address
ghavamzadeh_s@umsu.ac.ir
Recruitment status
Recruitment complete
Funding source
Uremia University of Medical Sciences
Expected recruitment start date
2015-10-01, 1394/07/09
Expected recruitment end date
2015-10-22, 1394/07/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison effect of omega-3 supplementation on postpartum depression and serum homocysteine of lactating women and growth and development of their infants
Public title
Effect of omega3 supplementation during lactation on postpartum depression and growth and development of infant
Purpose
Supportive
Inclusion/Exclusion criteria
Including criteria: lactating women who have moderate depression; have singleton and term birth; have no complicated pregnancy and labor; have no history of depression and use antidepressants or anticoagulants; age of mother between 18-35; weight of infants above 2500 grams.
Excluding criteria: lactating women who have severe depression; have preterm birth and twins; have chronic diseases such as blood pressure and diabetes; have complicated pregnancy and labor; ages of mothers under 18 years old and above 35 years old.