Children -parents dissociation and enterance to the operating room are accompanied with anxiety which causes unwished intra and postoperative complications.Postoperative agitation, pain, nausea and vomiting are other problems that reducing and controlling them, is one of the aims of an anesthesiologist.The purpose of this study is to compare the effect of intranasal dexmedetomidine, midazolam and ketamine on preoperative sedation and postoperative nausea, vomiting and pain and as a result, decreasing the hospital cost, shorter recovery stay and early return of children to daily activity.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2013081614372N1
Registration date:2014-02-11, 1392/11/22
Registration timing:retrospective
Last update:
Update count:0
Registration date
2014-02-11, 1392/11/22
Registrant information
Name
Simin Azemati
Name of organization / entity
Shiraz University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 71 1647 4270
Email address
azemati@sums.ac.ir
Recruitment status
Recruitment complete
Funding source
Shiraz University of Medical Sciences,vice chancellor of research
Expected recruitment start date
2013-07-23, 1392/05/01
Expected recruitment end date
2013-12-21, 1392/09/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
comparison of sedative effect of intranasal Dexmedetomidine,Midazolam and Ketamine in outpatient pediatric surgeries
Public title
comparison of sedative effect of Dexmedetomidine,Midazolam and Ketamine in outpatient pediatric surgeries
Purpose
Treatment
Inclusion/Exclusion criteria
inclusion criteria: children aged between 2-7 year; ASA classification I-II; unilateral inguinal herniorraphy
Exclusion criteria: Hx. of hypersensitivity to drugs of the study(Midazolam; Ketamine and Dexmedetomidine); liver failure; renal failure; upper respiratory tract infection; cardiac arrythmia; congenital heart disease; neurologic disease
Age
From 2 years old to 7 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
90
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics Committee of Shiraz University of Medical Sciences
Street address
Vice Chancellor for research ; Shiraz University of Medical Sciences ,Zand street