The effect of Ocimum Basilicium oil on pain and headache in patient who has migraine

Determination of the effect of Basil on the severity of headache and the frequency of recurrence of headache attacks (the number of migraine attacks over a period of six months) in migraine headache patients

The clinical trial has four types of experimental and control group, each of which is 36, is community based and pragmatic, with parallel groups, blind, randomized

Diagnosis was performed by a neurologist at a specialized clinic Rahimi Hospital (Khorramabad-Iran). Essential oil extraction method of Basil plant, in the form of water extraction by water distillation. In all groups, routine treatment, which prescribed acetaminophen 325 for all groups, and only Acetaminophen 325, and other groups, were treated with Acetaminophen with different doses of essential oil of the Basal plant. Basil essential oil was prepared with doses of 2,4,6% and was provided to the patient for topical use on the forehead and every eight hours.

The study population of men and women with migraine headache referring to the Neurology Clinic of Rahimi Hospital (Khorramabad-Iran). In the period from the beginning of the second half of 2013 for a year The upper age limit of 18 years

Three groups of 36 patients in the experimental group received doses of 2, 4 and 6% of Basilicum and one group of 36, as the control group with 250 doses of Acetaminophen, with the composition of essential oil without the Basilic acid substance in the intervention groups. The experimental group was visited at the specified time intervals (second week, fourth week, second month, third month) by referring to the neurologist and according to designed questionnaires, the relapse rate and headache severity were measured.

Severity of pain and number of migraine attacks

Raziherbal Medicine Center

Randomization will achieve with using sample block method.The studied units will be assigned to the four groups according to the criteria for inclusion in the study and available on the basis of randomized blocking. The entry of individuals to each of the groups will be done in the order of the number of selected blocks and will be done using the layout inside the block.

Considering that one of the response variables (severity of pain) is highly dependent on the induction effects, the study is a three-point study. Also, to eliminate the effects of induction, an ophthalmic drug was used in the control group. In case of using the patient with other drugs, the patient was asked to complete the list of all used medications in the relevant form. To evaluate the outcome of the safety organization, no information was given on the dosage of medications and the expected results, so that the conditions could be genuinely evaluated.