Comparison of therapeutic effect of intravenous ketamine low doses versus pethidine on post spinal anesthesia shivering in patients undergoing elective cesarean section

The overall goal: Comparison of therapeutic effect of intravenous ketamine low doses versus pethidine on post spinal anesthesia shivering in patients undergoing elective cesarean section. Study design: random double blind Placebo controlled. Study population: the study population consisted of patients who were referred for elective cesarean Best Hospital operating room. Inclusion Criteria: being candidate for cesarean section; fill in consent forms; physical status class I or II in accordance with anesthesia. Exclusion Criteria: pregnancy associated with diseases such as hypertension, diabetes; heart valve disease; coronary artery disease; pulmonary hypertension;pre Eclampsia and Diabetes mellitus. Sample size and sampling: with respect to Type I error of 5%, power of 90%, 45%, and the incidence of shivering in a group of 25 patients in the placebo group versus 85% in this study, 45 patients in each group were calculated for each group examines Intervention or interventions studied: Pethidine group of 5/0 3 kg and ketamine / kg in a volume equal to 0 immediately after spinal anesthesia is injected intravenously. Presence or absence of chills and grade them 4-0 is determined based on.Grade zero: no chills. Grade1: mild fasciculation in the face and neck. Grade2: trembling visible muscle groups in more than one category. Grade 3: Zlany activity of the whole body is involved. Intervention: the drug intravenously then Immediately after injection of spinal anesthetic is injected. Then chill after surgery to assess patient access to measures of pain occurs. Primary outcome or outcomes studied: during surgery and recovery Any adverse effect if seen is recorded Adverse events (nausea, vomiting, nystagmus, hypotension requiring treatment, bradycardia requiring medication).

Research Office of Kurdistan University of Medical Sciences