This study is a single blind placebo- control clinical trial that will be done to aim of comparative study of the effect of fortified yogurt with vitamin D, plain yogurt and vitamin D supplement on Glycemic, lipid and anthropometric indices in patients referred to Taleghani Hospital Diabetic Clinic that recently they have been diagnosed with pre-diabetes condition. Sampling will be done the based on inclusion criteria and available sampling, then samples place randomly in three interventions, including fortified yogurt (100cc/day) with 1000 IU Vitamin D receiving group, vitamin D supplement (1000 IU/day) receiving group, plain yoghurt (100cc/day) receiving group. Inclusion criteria, including full consent of the individual, 25-65 years old, not family history of diabetes, lack of other chronic diseases (coronary heart, liver, kidney, thyroid, parathyroid, malabsorption, ...) or special circumstances such as pregnancy and breastfeeding, avoiding the use of any supplements or drugs and no smoking. Exclusion criteria, including lack of interest in the continuation of cooperation, failure to follow the consumption of specified amount of fortified yogurt with vitamin D, plain yogurt and vitamin D supplement and require to use of oral anti diabetic drug. The Intervention will be done for three months, before and three months after intervention are evaluated glycemic, lipids and anthropometric indices.
To collect the data will use of questionnaires, including demographic data and disease status, physical activity and food frequency questionnaire (FFQ). Also to collect anthropometric data will use of Body composition Analyzer .In order to investigation of the blood indices, including fasting blood glucose, HbA1c, 2h- OGTT, fasting insulin, vitamin D, ca, AST, ALT, TC, LDL-c, HDL-c and TG, will be take 10 cc of blood in the fasting state, before and three month after the intervention.
The study is in the recruitment phase.
Blinding will be done to Analysts of data.