The purpose of this clinical trial study was to compare the effects of Micosin vaginal cream with Miconazole vaginal cream for the treatment of mycotic vaginitis. This clinical trial was conducted on 120 women in their reproductive age who were diagnosed with candida vaginitis through clinical examinations and laboratory tests. Using randomized allocation method, the subjects were divided into two groups of 60 people. The participants in the first group were treated by Miconazole, while subjects in the second group were prescribed Micosin. Patients in both groups were asked to apply the drug once a day for seven consecutive days. After seven days of therapy, patients were re-examined through clinical and laboratory tests to compare the results.
Inclusion criteria: women with Symptoms of Candida vaginitis infection in reproductive age.
Exclusion criteria: any history of taking antibiotics or immunosuppressive drugs or vaginal medications during the four weeks prior to the start of the study; diagnosis with cervicitis; suffering from candida vaginitis for more than 3 times a year; pelvic inflammatory disease; pregnancy or menopause; patients with high risk conditions (such as diabetes, anemia, obesity, overt autoimmune disease, coagulation disorders); history of allergic reaction to garlic or cream of vaginal azole class; improper application of the medication; refusal to pay follow-up visits; personal decision by patients not to participate in the study.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2013120715697N1
Registration date:2014-03-02, 1392/12/11
Registration timing:retrospective
Last update:
Update count:0
Registration date
2014-03-02, 1392/12/11
Registrant information
Name
Shiva Alizadeh
Name of organization / entity
Islamic Azad university of rasht
Country
Iran (Islamic Republic of)
Phone
+98 13 1422 2154
Email address
gelayolalizadeh@iaurasht.ac.ir
Recruitment status
Recruitment complete
Funding source
Research Deputy of Islamic Azad University of Rasht
Expected recruitment start date
2013-05-07, 1392/02/17
Expected recruitment end date
2013-09-12, 1392/06/21
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of Micosin vaginal cream compared to Miconazole vaginal cream for the treatment of mycotic vaginitis
Public title
Effect of Micosin vaginal cream compared to Miconazole vaginal cream for the treatment of mycotic vaginitis
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: women with Symptoms of Candida vaginitis infection in reproductive age.
Exclusion criteria: any history of taking antibiotics or immunosuppressive drugs or vaginal medications during the four weeks prior to the start of the study; diagnosis with cervicitis; suffering from candida vaginitis for more than 3 times a year; pelvic inflammatory disease; pregnancy or menopause; patients with high risk conditions (such as diabetes, anemia, obesity, overt autoimmune disease, coagulation disorders); history of allergic reaction to garlic or cream of vaginal azole class; improper application of the medication; refusal to pay follow-up visits; personal decision by patients not to participate in the study.
Age
From 16 years old to 49 years old
Gender
Female
Phase
2-3
Groups that have been masked
No information
Sample size
Target sample size:
120
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Islamic Azad University of Rasht
Street address
Department of Midwifery; Islamic Azad University of Rasht; Pole Taleshan; Rasht; Guilan; Iran