Assessing the effect of Olea ointment (a compound of honey, olive, and sesame) on infection and granulation tissue formation in second degree burn wounds - A randomized clinical trial

Objectives: This study aimed to investigate the effect of Olea ointment (topical honey ointment) in preventing infection and speeding up the formation of granulation tissue in the second degree burn. Design: 30 patients who had second degree burns (burn depth of 0.2 to 5.0 mm) were investigated as the study population. Setting and conduct: This was a randomized controlled trial which was conducted in the burn ward in Tohid hospital in Sanandaj. The patients were divided into two groups using simple randomized method (using computer); the chance of entering the control group was twice as that of the intervention group. Thus 20 patients were allocated in the control group and 10 patients were allocated in the intervention group. Participants and inclusion and exclusion criteria: According to inclusion criteria people with second degree burns and with burns equal or less than 40% of body surface area were enrolled in the study. Patients with underlying conditions such as diabetes, chronic renal or hepatic diseases, and patients with burns and concomitant trauma, and with concomitant skin tears were excluded. Interventions: One of the groups was treated on a daily basis using topical Olea ointment (FaraTeb Co, Iran) and the other group using Acetate Mafenide ointment (8.5%, Sina Daru, Iran). Main outcome variables: Wound infection and granulation tissue formation were considered as the main outcomes.

Kurdistan University of Medical Sciences