(1) Objectives: The effect of cardamom supplementation on blood oxidative stress status and inflammatory factors in overweight and obese prediabetic women, (2) Design: This study is a randomized double blind clinical trial, (3) Setting and conduct: People selected from pre diabetic women referred to the tow health centers of Karaj city after getting a written informed consent and considering the inclusion and exclusion criteria, (4) Participants including major eligibility criteria: - Inclusion criteria: Having at least one of this criteria, FBS; 100-125 mg/dl, HbA1C: 5.7-6.4, 2hpp blood glucose: 140-199 mg/dl; Age: 30-70 years; BMI: 25-39.9 kg/m2; Having at least one of the following criteria: TG>150 mg/dl, Chol>200 mg/dl, LDL>100 mg/dl, HDL<50 mg/dl. -Exclusion criteria: Multi vitamin and anti oxidant supplements consumption during the intervention; Changes in diet or physical activity; Not intaking of more than 10% of supplements; Morbidity to diabetes during the intervention, (5) Intervention: 80 subjects randomly assign to tow groups (40 intervention and 40 control groups). Intervention group receives 3 gr of green cardamom daily and placebo group receives 3 gr of rusk powder from 3 capsules (1 gr) tree times a day with meals. Period of intervention is 2 months, (6) main outcome measures (variables): Anthropometric measurements are performed by standard methods. Systolic and diastolic blood pressure are measured before and after the intervention in fasting state. Blood sample is taken from patient and GR, SOD, Total Antioxidant Capacity, MDA, Protein Carbonyl, IL-6, hs-CRP and TNF-α is measured before and after the study. General questionnaire, 24h dietary recall and physical activity questionnaire (IPAQ short form) are completed before and after the intervention. People are followed up by phone each week. The study compliance will be assumed through counting consumed capsules.