Comparison of the effect of Sufentanil in combination with Bupivacaine or Epinephrine and Bupivacaine alone in patients under spinal anesthesia on onset and recovery of motor and sensory block for lower extremity surgeries

The aim of this study is comparison of the effect of Sufentanil in combination with Bupivacaine or Epinephrine and Bupivacaine alone in patients under spinal anesthesia on onset and recovery of motor and sensory block for lower extremity surgeries. In this double blind randomized clinical trail study ninety patients computerized divided into equal tree groups. inclusion criteria: patients with lower extremity surgery; patients classified in American association of anesthesiologist one and tow groups; all patients between 18 to 50 years old. exclusion criteria: all patients reject spinal anesthesia; shock; sepsis; fever; coagulation system dysfunction; opium addiction; local infection in site of spinal needle insertion. spinal anesthesia perform in the first group with fifteen milligrams of bupivacaine adding 5 micrograms of sufentanil, in second group fifteen milligrams of bupivacaine adding ten microgram epinephrine and in the third group fifteen milligrams of bupivacaine adding one milliliter normal saline as a placebo. after spinal anesthesia sensory and motor block is measure every one minutes for 20 minutes and onset of sensory block, onset of motor block note. recovery from sensory block and recovery from motor block are measure after one hour after start for every 5 minutes and note. also six hour after surgery pain is measure with visual analog scale.

Birjand University Of Medical Sciences