Objective: Comparison of efficacy and side effects of topical 15% potassium hydroxide solution and cryotherapy in treatment of common wart
Design: Non- randomized; non- blinding
Inclusion criteria: common wart with a diameter less than 5mm ; on the hands or feet bilaterally
Exclusion criteria: pregnancy; lactation; treatment during one recent month; secondary skin infection
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2014081118765N1
Registration date:2014-12-12, 1393/09/21
Registration timing:retrospective
Last update:
Update count:0
Registration date
2014-12-12, 1393/09/21
Registrant information
Name
Salah shohani
Name of organization / entity
jundishapur scientific medical university of ahvaz
Country
Iran (Islamic Republic of)
Phone
+98 61 1336 7543
Email address
shohani.s@ajums.ac.ir
Recruitment status
Recruitment complete
Funding source
Ahvaz Jundishapur University of Medical Sciences
Expected recruitment start date
2012-09-22, 1391/07/01
Expected recruitment end date
2013-03-15, 1391/12/25
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of efficacy and side effects of topical 15% potassium hydroxide solution and cryotherapy in the treatment of common wart.
Public title
Treatment of common warts with topical solution of potassium hydroxide 15%
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: patient who have common wart with diameter less than 5 mm, on the hand or foot bilaterally.
Exclusion criteria: pregnancy; lactation; treatment during one recent month; secondary skin infection
Age
From 3 years old to 60 years old
Gender
Both
Phase
2-3
Groups that have been masked
No information
Sample size
Target sample size:
29
Randomization (investigator's opinion)
Not randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ahvaz Jundishapur University of Medical Sciences
Street address
Ahvaz Jundishapur University of Medical Sciences, Golestan Street, Ahvaz, Iran
City
Ahvaz
Postal code
6135715794
Approval date
2012-05-26, 1391/03/06
Ethics committee reference number
672/D
Health conditions studied
1
Description of health condition studied
Common wart
ICD-10 code
I-B07
ICD-10 code description
Verruca Vulgaris
Primary outcomes
1
Description
Reduced size of Common warts
Timepoint
Before intervention. Every week from starting of intervention to disappearance of all warts. Two months after the end of intervention.
Method of measurement
observation; Ruler
Secondary outcomes
1
Description
Side effects
Timepoint
Before intervention. Every week from starting of intervention to disappearance of all warts. Two months after the end of intervention
Method of measurement
observation
Intervention groups
1
Description
Intervention group: Drug: Topical solution of 15% Potassium hydroxide Direct education to patients.
Period of application: Disappearance of warts
Application: Cotton swap weltering in solution of KOH 15% then put on each wart for 20 seconds, twice a day.
Category
Treatment - Drugs
2
Description
Control group :Treatment with cryotherapy
Application: One cotton swap be drowned in to nitrogen liquid then put on each wart for ten seconds and repeat it twice.