Comparision The effect of premedication with Acifen and Dexamethasone on the success of inferior alveolar nerve block for first and second molar teeth with symptomatic irreversible pulpitis
Aim of this study is comparision the effect of premedication with Acifen and Dexamethasone on the success of inferior alveular nerve block for first and second molar teeth of mandible with symptomatic irreversible pulpitis.
Inclusion criteria: patient with first or second molar teeth of mandible with symptomatic irreversible pulpitis, non systematic disease, non allergic patient to Lidocaine with 1:80000 Epinephrine, non allergic patient to NSAIDs, non allergic patient to Caffeine, non periapical radiolucency, non analgesic drug consumption 12 hours before treatment, non tooth with full crown
Exclusion criteria: non numles of lower lip, partial necrose of tooth
In this randomize double blind clinical trial study population are patients will be refer to General Endodontic Department of Dentistry School of Qazvin University of Medical Science of Iran.
The patients will be divide into 3 groups and random assignment.Patients will receive randomly one identical capsules contain .5 mg demamethasone or acifen or placebo 45 minutes before administration of a conventional IAN block.Access will begin 15 minutes after complation of IAN block for patient with lower lip numbness.success will define as no or mild pain according to visual analogue scale recordings on access cavity
Sample size: 150
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2014082618941N1
Registration date:2014-10-25, 1393/08/03
Registration timing:prospective
Last update:
Update count:0
Registration date
2014-10-25, 1393/08/03
Registrant information
Name
Ehsan Kamani
Name of organization / entity
University
Country
Iran (Islamic Republic of)
Phone
+98 28 3367 7908
Email address
ekamani@qums.ac.ir
Recruitment status
Recruitment complete
Funding source
General Endodontic Department of Dentistry School of Qazvin University Medical Science of Iran
Expected recruitment start date
2014-11-01, 1393/08/10
Expected recruitment end date
2014-12-31, 1393/10/10
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparision The effect of premedication with Acifen and Dexamethasone on the success of inferior alveolar nerve block for first and second molar teeth with symptomatic irreversible pulpitis
Public title
Comparision The effect of premedication with Acifen and Dexamethasone on the success of mandible nerve block in first and second molar teeth of mandible with symptomatic irreversible pulpitis
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: patient with first or second molar teeth of mandible with symptomatic irreversible pulpitis, non systematic disease, non allergic patient to Lidocaine with 1:80000 Epinephrine, non allergic patient to NSAIDs, non allergic patient to Caffeine, non periapical radiolucency, non analgesic drug consumption 12 hours before treatment, non tooth with full crown
Exclusion criteria: non numles of lower lip, partial necrose of tooth
Age
From 15 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
150
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Dentistry School of Qazvin University of Medical Science
Street address
University of Medical Science, Shahid Bahonar st
City
Qazvin
Postal code
Approval date
2014-09-15, 1393/06/24
Ethics committee reference number
28/20/9176
Health conditions studied
1
Description of health condition studied
Irrevesible pulpitis
ICD-10 code
K04.0
ICD-10 code description
Pulpitis
Primary outcomes
1
Description
Pain
Timepoint
45 minutse before access cavity preparation and during access cavity preparation
Method of measurement
visual analog scale
Secondary outcomes
empty
Intervention groups
1
Description
Dexamethasone group: .5 mg oral dexamethasone 30 minute before injection