Objectives: Recovery units in the operating rooms perform a part of the work done in the post anesthesia care unit since the patients transfer to the relative ward after stabilization of cardiovascular and respiratory state, maintaining full consciousness, and ability to move limbs. Discharge rate of these patients and the sustainability of organs can vary depending on the type of anesthesia and used drugs and affects discharge of patients from recovery. To improve hemodynamic parameters and consciousness of patients undergoing posterior lumbar spine fusion surgery, we compare two combinations include dexmedetomidine and propofol versus remifentanil and propofol.
Design: Block randomization, double blind, without placebo, single center, trial phase 2, including 20 patients who undergo posterior lumbar spine fusion surgery.
Setting and conduct: Fentanyl, 2 μg/kg, intravenous, to induce anesthesia.
Atracurium, 0.2 mg/kg, intravenous, to induce anesthesia.
Participants including major eligibility criteria: All women who are supposed to undergo posterior lumbar spine fusion surgery.
Intervention: Dexmedetomidine, 0.1 μg/kg, intravenous.
Remifentanil, 1 μg/kg, intravenous.
Propofol, 2 mg/kg, intravenous, to induce anesthesia.
Main outcome measures: Activity level, Respiration, Consciousness, Blood pressure, O2 saturation.