The main purpose of this study is to investigate effects of 8-week different combined training on serum levels of IL-6 and TNF-α in aged women. This study is a quasi-experimental research, 60 retired elderly woman of Education select purposely and randomly place into four groups of 15 subjects: endurance plus strength training, strength plus endurance training, interval concurrent training and control groups then the weight, height, body mass index, body fat percentage and Blood sample will be measure. Training programs will be perform for eight week, 3 times per week. Endurance training program Include a cycle ergo-meter and strength training program Include several upper and lower body workout. Forty-eight hours after the last training session all variables will be measured as per-test.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2014121019995N2
Registration date:2014-12-25, 1393/10/04
Registration timing:retrospective
Last update:
Update count:0
Registration date
2014-12-25, 1393/10/04
Registrant information
Name
Zahra Mardanpour Shahrekordi
Name of organization / entity
Shahrekord University
Country
Iran (Islamic Republic of)
Phone
+98 38 3232 4401
Email address
banitalebi@lit.sku.ac.ir
Recruitment status
Recruitment complete
Funding source
Investigator
Expected recruitment start date
2014-03-07, 1392/12/16
Expected recruitment end date
2014-04-07, 1393/01/18
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effects of 8-week different combined training (strength and endurance) on serum levels of IL-6, TNF-α in aged women
Public title
Effects of 8-week different combined training in aged women
Purpose
Diagnostic
Inclusion/Exclusion criteria
Inclusion criteria: female; 58 to 70 years; without experience of regular physical activity in one year before beginning of the study; the level of physical and mental health Exclusion criteria: history of cardiovascular diseases; cancer; high blood pressure; diabetes; thyroid disease; addiction to any smoking, alcohol and narcotic substances; Hormonal disorders; kidney or liver disease; surgery any medical intervention affecting the experimental results
Age
From 58 years old to 70 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
60
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
The effect of sequence order of combined training (resistance and endurance) on the body performance of older women
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Shahrekord University
Street address
Rahbar Blvd, Shahrekord
City
Shahrekord
Postal code
Approval date
2014-03-06, 1392/12/15
Ethics committee reference number
190/579م پ
Health conditions studied
1
Description of health condition studied
Relationship of sequence order of combined training (resistance and endurance) on Inflamm-aging
ICD-10 code
R54
ICD-10 code description
Senility
Primary outcomes
1
Description
IL-6
Timepoint
Before and after 8 weeks of intervention
Method of measurement
ELISA kit for Interleukin-6
2
Description
TNF-α
Timepoint
Before and after 8 weeks of intervention
Method of measurement
ELISA kit for TNF-α
Secondary outcomes
1
Description
Fasting glucose
Timepoint
Before and after 8 weeks of intervention
Method of measurement
ELISA kit for Fasting glucose
2
Description
Insulin
Timepoint
Before and after 8 weeks of intervention
Method of measurement
ELISA kit for Insulin
3
Description
Insulin resistance
Timepoint
Before and after 8 weeks of intervention
Method of measurement
The insulin resistance index by the (HOMA-IR) formula.
Intervention groups
1
Description
The endurance plus strength training group follow an combined training program for 8 weeks Who in the first do endurance training program and then 2 minutes of rest do strength training program.
Category
Other
2
Description
The strength plus endurance training group follow an combined training program for 8 weeks Who in the first do strength training program and then 2 minutes of rest do endurance training program.
Category
Other
3
Description
The interval training group do rotating E plus S plus E plus S plus E plus S training programs , so that's the strength and endurance program was divided into three parts.
Category
Other
4
Description
The control group do not any regular physical activity in Daily life.
Category
Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Department of Education region 1 of Shahrekord city
Full name of responsible person
Street address
City
Shahrekord
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Shahrekord University
Full name of responsible person
Dr Ebrahim Banitalebi
Street address
Rahbar Blvd, Shahrekord
City
Shahrekord
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Shahrekord University
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Shahrekord University
Full name of responsible person
Dr Ebrahim Banitalebi
Position
Ph.D of Sport Physiology/Assistant Professor
Other areas of specialty/work
Street address
Rahbar Blvd, Shahrekord
City
Shahrekord
Postal code
Phone
+98 38 3232 4401
Fax
Email
Banitalebi@lit.sku.ac.ir
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Shahrekord University
Full name of responsible person
Dr Mohammad Faramarzi
Position
Ph.D, of Sport Physiology/Associate Professor
Other areas of specialty/work
Street address
Rahbar Blvd, Shahrekord
City
Shahrekord
Postal code
Phone
+98 38 3232 4401
Fax
Email
md.faramarzi@gmail.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Shahrekord University
Full name of responsible person
Zahra Mardanpour Shahrekordi
Position
MSc, Applied Exercise Physiology
Other areas of specialty/work
Street address
Rahbar Blvd, Shahrekord
City
Shahrekord
Postal code
Phone
00
Fax
Email
zahramardanpour@gmail.com
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)