Aim of this study is to compare the efficacy of nano crystalline silver dressings compared with conventional dressings in patients with impaired upper limb crushed fingers. This study is clinical trials and double blind. Inclusion criteria: age 18 to 70 years with Finger injury with damage to the muscle of the upper limb; crush injury in 10 to20 centimeter in muscles. Exclusion criteria: involvement of tendons, blood vessels, muscles, nerves and bones at the site of damage; systemic diseases such as cardiovascular disease, metabolic disorders, collagen vascular, immunosuppression (diabetes, transplant) malignant; inflammatory and infectious diseases at the same time; malnutrition (important in wound healing); addiction; pregnancy; breastfeeding; need for limb amputation; Loss of consciousness and traumatic brain injury; need for further surgery on the wound; history of skin allergy to silver; infected wounds before applying the dressing at first stage. there are 70 patients . We will divide patients in to two groups randomly. We treat 35 patients with nano crystalline silver in intervention group. We treat 35 patients with normal wound dressing in control group. We will follow the wound improvement at the end of first, second, third and fourth visits (4 times) after surgery. We will follow-up by phone.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2017021520258N33
Registration date:2017-03-06, 1395/12/16
Registration timing:registered_while_recruiting
Last update:
Update count:0
Registration date
2017-03-06, 1395/12/16
Registrant information
Name
Fariba Farokhi
Name of organization / entity
Arak University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 86 3222 2003
Email address
f.farokhi@arakmu.ac.ir
Recruitment status
Recruitment complete
Funding source
Vice Chancellor and research, Arak University of Medical Sciences
Expected recruitment start date
2016-06-14, 1395/03/25
Expected recruitment end date
2017-06-15, 1396/03/25
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Compare the efficacy of nanocrystalline silver dressings compared with conventional dressings in patients with impaired upper limb crushed fingers
Public title
Compare the efficacy of nanocrystalline silver dressings compared with conventional dressings in patients with impaired upper limb crushed fingers
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: age 18 to 70 years with Finger injury with damage to the muscle of the upper limb; crush injury in 10 to20 centimeter in muscles.
Exclusion criteria: involvement of tendons, blood vessels, muscles, nerves and bones at the site of damage; systemic diseases such as cardiovascular disease, metabolic disorders, collagen vascular, immuno suppression (diabetes, transplant) malignant; inflammatory and infectious diseases at the same time; malnutrition (important in wound healing); addiction; pregnancy; breastfeeding; need for limb amputation;Loss of consciousness and traumatic brain injury; need for further surgery on the wound; history of skin allergy to silver; infected wounds before applying the dressing first stage
Age
From 18 years old to 70 years old
Gender
Both
Phase
2-3
Groups that have been masked
No information
Sample size
Target sample size:
70
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Randomize by table of random numbers
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics committee Arak University Of Medical Sciences