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Study aim
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Determine the comparative effect of continuous versus pulsative flushing on the phlebitis incidence, patency and longevity of peripheral intra venous catheter in patients admitted to medical and surgical wards of Eesfarayen Hospital
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Design
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A clinical trial study of three groups, single blind and randomize assignment.
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Settings and conduct
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After obtaining Ethics Committee permission and permission from Esfarayn faculty of Medical Sciences and the officials of Imam Khomeini Esfarayn Hospital, first choose sample selection with form then eligible patients were selected using a goal-based sampling method and then explained. The purpose of the research and how it will be done, the patients will receive written consent to participate in the research, and they will be informed that they can be dissuaded from continuing to participate in the research whenever they wish.
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Participants/Inclusion and exclusion criteria
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The participants of this study are patients admitted to the internal and surgical wards of Imam Khomeini Hospital Esfarayne. inclusion includes patients18 to 65 years old that hospitalized for at least 96 hours and exclusion criteria including taking an anticoagulant drugs.
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Intervention groups
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In the first intervention group (pulsative flushing), before injection of the first drug into the intravenous catheter, five milli liter(m.l) of the 0.9% Nacl solution, which Pre-prepared into 5-m.l syringe,put up top of the catheter that had one-way valve.Then, one m.l of the solution is injected into the catheter within one second, then 0.4 seconds is interrupted and again one m.l is injected within one second, this procedure continues until the evacuate five milliliters 0.9% Nacl solution.Then the patient's drug is injected in accordance with the leaflet or the physician's order، After the drug is finished, if they have another drug, before the second drug is injected, the pulsative Flushing method described above is repeated and then the second drug is injected.
These steps will continue until patient medications to be completed . Finally, locking technique performed(one m.l of 0.9% Nacl solution is slowly injected with a two m.l syringe through heparin lock that located at the end of the p.v.c) and the patient's catheter until the next patient's drug is administered remains intact(minimum time is six hours from the last injection).
In the second intervention group (pulsative flushing), before injection of the first drug into the intravenous catheter, five milli liter(m.l) of the 0.9% Nacl solution, which Pre-prepared into 5-m.l syringe,put up top of the p.v.c that had one-way valve.
Injection will be done within 5 seconds.Then the patient's drug is injected in accordance with the leaflet or the physician's order، After the drug is finished, if they have another drug, before the second drug is injected, the continous flushing method described above is repeated and then the second drug is injected. finally locking technique performed.
In the control group, drugs are injected at a predetermined time.
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Main outcome variables
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Peripheral catheter phlebitis: The patient score obtains from a phlebitis visual check list.
patency of p.v.c : Lack of resistance to drug injection with or without blood return.
Longevity of p.v.c : period of time which there is not evidence shows the catheter functional ended or catheter is not prohibited, time will be recorded per hours(maximum time is 96 hours).