According to current knowledge, several studies has been conducted separately concerning the relationship between garlic and lemon juice in reducing inflammatory biomarkers and lipid profile in patients with cardiovascular disease. But yet, the effects of garlic and lemon juice mixture over the indices of cardiovascular disease is not analyzed, and regarding the high and increasing prevalence of these diseases in the world and in Iran, the aim of present study is to investigate effect of garlic and lemon juice mixture on lipid profile and some cardiovascular risk factors.people with hyperlipidemia according to the inclusion criteria were selected and randomly divided into 4 groups and control blood samples were taken, height, weight and blood pressure were recorded, first group received 20 grams of garlic daily, plus 1 tablespoon lemon juice, second 20 g garlic daily , third group 1 tablespoon lemon juice daily2 hours after dinner and forth group did not receive garlic and lemon juice during the intervention. Experiments were repeated after 2 month, the results were analyzed the SPSS softwere.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2015020720986N1
Registration date:2015-03-07, 1393/12/16
Registration timing:retrospective
Last update:
Update count:0
Registration date
2015-03-07, 1393/12/16
Registrant information
Name
Negar Aslani
Name of organization / entity
Isfahan Univercity Of Medical Science
Country
Iran (Islamic Republic of)
Phone
+98 31 3433 2929
Email address
negar_aslani@nutr.mui.ac.ir
Recruitment status
Recruitment complete
Funding source
Vice chancellor for research, Isfahan University of Medical Science
Expected recruitment start date
2013-10-23, 1392/08/01
Expected recruitment end date
2013-12-22, 1392/10/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of garlic and lemon juice mixture on lipid profile and some cardiovascular risk factors in people 30-60 years old with hyperlipidemia.
Public title
Effect of mixed of garlic and lemon juice on hyperlipidemia
Purpose
Treatment
Inclusion/Exclusion criteria
Subjects were eligible if they have a total cholesterol and LDL levels between 240-200 mmol/l and 160-100 mmol/l respectively. People should not be suffering from any other diseases, including heart problems, kidney, lung, thyroid disorders, gastrointestinal, rheumatoid arthritis and other liver problems such as hepatitis or fatty liver, pregnancy or lactating, no smoking, their weight may not change fast in the last two months, should not use drugs that affect blood sugar, blood fat, blood pressure and anti-inflammatory and not to have any sensitivity to garlic and lemon juice. Individual with a history of chronic disease, consuming medicine and flowing special regimen were excluded.
Age
From 30 years old to 60 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
120
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethical Committee of Isfahan University of Medical Sciences
Street address
Isfahan University of Medical Sciences, Hezar jarib street
City
Isfahan
Postal code
Approval date
2013-10-28, 1392/08/06
Ethics committee reference number
392436
Health conditions studied
1
Description of health condition studied
Hyperlipidemia
ICD-10 code
E78.0
ICD-10 code description
Disorders of lipoprotein metabolism and other lipidaemias