The effect of non-surgical periodontal treatment with diode laser or photodynamic therapy with Emundo mixture on clinical and microbiological indices in patients with chronic periodontitis

Objectives: The purpose of present study is to evaluate the impact of non-surgical laser therapy and photodynamic therapy on chronic periodontitis. Design: In this randomized clinical trial, twenty patients with chronic periodontitis were selected among the patients referring to Isfahan University of medical sciences by convenience sampling. Setting and Conduct: Mechanical debridement was accomplished for the whole mouth. Applying a split-mouth design, each quadrant was randomly treated with one of the therapeutic interventions. This randomization was done with table of randomization numbers. Participants: the patients should be systemically healthy and no smoker. Interventions: therapeutic interventions including 1- mechanical debridement alone, 2- mechanical debridement +laser therapy, or 3- mechanical debridement + photodynamic therapy were accomplished in 2 sessions within 2 weeks. Variables: The clinical indices including, pocket probing depth, clinical attachment level, papillary bleeding index and plaque index were measured at baseline, 6 weeks and 3 months after treatment. Microbiological samples were taken and evaluated at baseline and 3-month follow-up. Triple blinding during the study procedure was performed for patient (by placebo treatment in other quadrants), researcher and data monitoring committee (by unawareness of intervention process).

Vice chancellor for research, Faculty of Dentistry, Isfahan University of Medical Sciences.