The aim of the present study was to investigate the effect of one session resistance exercise on markers of muscle damage and hemodynamic changes in anabolic steroids user professional bodybuilders. Inclusion criteria: male; 22-30 years old; healthy; bodybuilding athletes;at least 5 years professional bodybuilding background. Exclusion criteria: Diseases; Injuries.
In this semi-experimental study 20 bodybuilders (22-23 yrs), who had the experience of at least 5 years resistance training, were assigned to two groups including anabolic steroid group and non-steroid group. All participants performed a single bout of circuit resistance exercise. Blood samples were taken before exercise, immediately after exercise and 24 hours following exercise to be measured for serum levels of CK and LDH. Hemodynamic measurements including blood pressure and heart rate were done in the aforementioned times.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2015040621625N1
Registration date:2015-06-29, 1394/04/08
Registration timing:registered_while_recruiting
Last update:
Update count:0
Registration date
2015-06-29, 1394/04/08
Registrant information
Name
Azadeh Nasseri
Name of organization / entity
University of Tabriz
Country
Iran (Islamic Republic of)
Phone
+98 41 3442 4470
Email address
naseri_azadeh@yahoo.com
Recruitment status
Recruitment complete
Funding source
University of Tabriz
Expected recruitment start date
2015-05-26, 1394/03/05
Expected recruitment end date
2015-06-30, 1394/04/09
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of one session resistance exercise on markers of muscle damage and hemodynamic changes in anabolic steroids user professional bodybuilders
Public title
Effects of AAS and resistance training on muscle damage and hemodynamic characteristics
Purpose
Basic scienece
Inclusion/Exclusion criteria
Inclusion: male; 22-30 years old; healthy; bodybuilding athletes; BMI <26;at least 5 years profesional bodybuilding background. Exclusion: Diseases; Injuries.
Age
From 22 years old to 30 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
16
Randomization (investigator's opinion)
Not randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Tabriz University of Medical Sciences
Street address
Golgasht St. Daneshgah St. Tabriz, East Azerbaijan, Iran
City
Tabriz
Postal code
Approval date
2015-05-25, 1394/03/04
Ethics committee reference number
TBZMED.REC.1394.154
Health conditions studied
1
Description of health condition studied
Exercise-induced physiological stress
ICD-10 code
Z03.5, Z03
ICD-10 code description
Unspecified adverse effect of drug or medicament
Primary outcomes
1
Description
creatine kinase
Timepoint
immediately before the exercise session; immediately after the exercise session; 24-h following the exercise session
Method of measurement
spectrophotometry
2
Description
lactate dehydrogenase
Timepoint
immediately before the exercise session; immediately after the exercise session; 24-h following the exercise session
Method of measurement
spectrophotometry
3
Description
heart rate
Timepoint
immediately before the exercise session; immediately after the exercise session; 24-h following the exercise session
Method of measurement
polar heart rate monitors
4
Description
blood pressure
Timepoint
immediately before the exercise session; immediately after the exercise session; 24-h following the exercise session
Method of measurement
cuff devise
Secondary outcomes
empty
Intervention groups
1
Description
The subjects of AAS-user group(self-directed users) will participate in a circuit strength exercise session involved three sets of 6-9 repetitions at 80-85% of 1-RM.
Category
Other
2
Description
The subjects of AAS-non user group (control group) will participate in a circuit strength exercise session involved three sets of 6-9 repetitions at 80-85% of 1-RM.
Category
Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Athletics Board of Tabriz Bodybuilding
Full name of responsible person
Saeed Nikookheslat
Street address
City
Tabriz
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
University of Tabriz
Full name of responsible person
Dr. Saeed Nikookheslat
Street address
Faculty of Physical Education and Sport Sciences, University of Tabriz, 29 Bahman Street
City
Tabriz
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
University of Tabriz
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
University of Tabriz
Full name of responsible person
Dr Saeed Nikookheslat
Position
PhD/ Associate Professor of Exercise Physiology
Other areas of specialty/work
Street address
29 Bahman Ave. University of Tabriz, Faculty of Physical Education and Sport Sciences
City
Tabriz
Postal code
Phone
+98 41 1339 3255
Fax
Email
naseri_azadeh@yahoo.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
University of Tabriz
Full name of responsible person
Azadeh Nasseri
Position
MS.c in Sports Physiology
Other areas of specialty/work
Street address
29 Bahman Ave. University of Tabriz, Faculty of Physical Education and Sport Sciences
City
Tabriz
Postal code
Phone
+98 41 1339 3255
Fax
Email
naseri_azadeh@yahoo.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
University of Tabriz
Full name of responsible person
Azadeh Nasseri
Position
MSc in Sports Physiology
Other areas of specialty/work
Street address
29 Bahman Ave. University of Tabriz, Faculty of Physical Education and Sport Sciences
City
Tabriz
Postal code
Phone
00
Fax
Email
naseri_azadeh@yahoo.comazad.naseri@gmail.com
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)