The present study is a clinical trial with a pretest-posttest design. After random selection and assignment of samples to control and 2 intervention groups( intervention groups-I and intervention groups-II).
Interventions:
intervention groups-I: para-cognitive therapy performs on the first intervention group during ten 1-hour sessions (a new method of psychotherapy that is mostly concerned with the effect of depression on thinking process than its content) , In this model, depression is associated with some kinds of Mal-adaptive thinking styles, known as Cognitive-Attention Syndrome. This syndrome is characterized by repetitive thought in the form of anxiety or rumination on a threat and Mal-adaptive coping behaviors.
Intervention groups-II: 10-60 mg citalopram ( a standard and widely used antidepressant from SSRI group of antidepressants) will be administer in a daily single dose, the drug will be started 10 mg/day and then will be increased weekly to optimum dose ( 20-60 mg/day).
Control group: do not receive any interventions and they will be place on waiting list. All the groups will be evaluate twice (pre-test, post-test ).
We invite volunteers to participate in the study from outpatients diagnosed with depression in treatment centers and clinics of Isfahan. Thereafter, the volunteers will be interviewed by psychologists and psychiatrists based on the symptoms proposed by Diagnostic and Statistical Manual of Mental Disorders(DAM-IV-TR) to reach a definitive diagnosis of major depression disorder. The eligible patients randomly divide into three groups of citalopram (n=15), para-cognitive intervention (n=15), and control (n=15).
A demographic form, which included items on age, gender, educational level, and occupation, will be used to gather demographic information. The following three questionnaires will be employed in this study, as well.
Beck depression inventory-II, para-cognition questionnaire-30, Cognitive emotion regulation questionnaire.