Dementia as a chronic progressive disorder is one of the main causes of disability in the old age that is associated with an epidemic and significant increase in recent years. The main symptom of dementia is progressive forgetfulness that gradually leads to disorders in thinking, judgment, orientation, learning, language, behavior and mood. Treatments include psychological therapies (cognitive, behavioral and supportive therapy) or cholinesterase inhibitors, NMDA receptor agonist and psychotropic drugs. In addition to the complications of medications, we have little Improvement and no effect on the course of the disease. That is why the traditional and complementary approaches have been developed . The word "Nesyan" in traditional term means to forget what was learned or inability to learn, which is similar to the modern concept of dementia. The cause in traditional term is dysfunction of the cerebral forces (Memory, thinking and imagination). "Ostokhodus" according to Iranian sages is a unique drug in empowering the brain, very effective in purification and purification, Nourishing mental and intellectual forces and useful in neuronal diseases. Recent studies in animal models proved it as a heating, antioxidant herbal remedy with anti-cholinesterase inhibitory effects. Therefore, this medicinal species selected to prove its effectiveness in human studies.