Comparison of the effect of intrathecal Bupivacaine and Fentanyl with Bupivacaine and Dexmedetomidine on post operative pain of cesarean section in Shariati Hospital of Bandar Abbas in 2014

Background and Objective: Pain is one of the most common post-operative complications. In the case of cesarean section the post-operative pain can result in some complications for both Mother and neonate. Many methods have been proposed for the post-operative pain. Intrathecal opioid or dexmedetomedine injections are two examples of these methods. The aim of this study is to compare the efficacy of intrathecal fentanyl and dexmedetomedine for post-operative analgesia in cesarean sections that took place in Shariati Hospital of Bandar Abbass during 2014. Method: Randomized with 2 blocks design is considered. Double blinding design will be provided by concealing the awareness of the patients and the researcher who is in charge of data collection from the type of intervention. A total of 110 pregnant women who are scheduled for elective cesarean section divided into two groups randomly. Inclusion criteria: Women between 15 and 45 years old; Gestational age 37 week or higher; ASA 1-2. Exclusion criteria: Emergency patients; patients with contraindication for regional anesthesia; patients with Valvular Heart Disease; patients with history of Allergy to local anesthetic drugs; addiction or alcoholism; Placenta Previa; patients with incomplete spinal block who require analgesic agents. Intervention: Group A received 10 mg bupivacaine 0.5% plus dexmedetomedine 5 microgram; group B received 10 mg bupivacaine 0.5% plus fentanyl 25 microgram intrathecally. Main measurable variables: pain score, and motor block time.

Vice chancellor for Research, Hormozgan University of Medical Sciences