Protocol summary

Summary
The aim of this study is Effect of herbal marine compound (HESE-A) on Quality of life in women with breast cancer Inclusion criteria: age above 18 years and below 60 years, diagnosis of breast cancer by oncologist and pathologist physician,History of at least one course of chemotherapy Exclusion criteria: Forgot pills Hesa - A for five consecutive times or more,Use of medication or other treatment methods to reduce the effects of other common medications prescribed by the doctor Single-blind, controlled study randomized clinical trial of chemotherapy at the center of the city of Bushehr on 72 women with breast cancer undergoing chemotherapy will be done. After selecting 72 female patients with breast cancer among all patients, 36 patients were divided into two groups: the intervention group (drug Hsa-A) and control group (placebo) will be. The intervention and control groups after chemotherapy treatments ، Hesa-a daily one tablet orally (50 mg) will start and lasts for three months and the control group patients received placebo capsules daily Through oral . Quality of life in patients before the intervention, 45 and 90 days after treatment is assessed via questionnaire

General information

Acronym
IRCT registration information
IRCT registration number: IRCT2015112322466N8
Registration date: 2016-01-31, 1394/11/11
Registration timing: registered_while_recruiting

Last update:
Update count: 0
Registration date
2016-01-31, 1394/11/11
Registrant information
Name
Shahnaz Pouladi
Name of organization / entity
Bushehr University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 917 374 0061
Email address
sh.pooladi@bpums.ac.ir
Recruitment status
Recruitment complete
Funding source
Bushehr University of Medical Sciences
Expected recruitment start date
2016-01-30, 1394/11/10
Expected recruitment end date
2016-07-31, 1395/05/10
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of herbal marine compound (HESE-A) on Quality of life in women with breast cancer in medical centers in Bushehr city in 1394
Public title
Effect of herbal marine compound (HESE-A) on Quality of life in women with breast cancer in medical centers in Bushehr city in 1394
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: age above 18 years and below 60 years, diagnosis of breast cancer oncologist and pathologist doctor (stage 3 and 4); history of at least one course of chemotherapy, no history of drug allergy Hsa-A Exclusion criteria from the study include: Forgot pills Hesa - A for five consecutive times or more, the use of drugs or other treatment methods to reduce the effects of other common medications prescribed by your doctor; the risk of problems and severe gastrointestinal side effects during the study, and eventually the desire to continue to participate in the study.
Age
From 18 years old to 60 years old
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 72
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
Placebo
Used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Bushehr University of Medical Sciences
Street address
Bushehr University of Medical Sciences, Bushehr Iran
City
Bushehr
Postal code
Approval date
2015-11-14, 1394/08/23
Ethics committee reference number
bpums.res.1394.23

Health conditions studied

1

Description of health condition studied
breast cancer
ICD-10 code
C50
ICD-10 code description
Malignant neoplasm of breast

Primary outcomes

1

Description
Quality of Life
Timepoint
Before the study, 45 days and 90 days after treatment
Method of measurement
questionnaire

Secondary outcomes

1

Description
Quality of Life
Timepoint
Before the study, 45 days and 90 days after treatment
Method of measurement
questionnaire

Intervention groups

1

Description
The control group received placebo capsules (identical in shape Hesa-a capsules) One capsule (50 mg) daily through orally for three months
Category
Placebo

2

Description
In the intervention group after a course of chemotherapy (second or more) on a daily basis Hesa-a orally one tablet (50 mg) will start for three months
Category
Treatment - Drugs

Recruitment centers

1

Recruitment center
Name of recruitment center
Hospital Bushehr Persian Gulf؛ Osfuri Doctor's office ؛ Ravanbod Doctor's office
Full name of responsible person
Roohollahesmati: Master Nursing Student
Street address
Amiralmomenin Hospital, Bushehr, Iran
City
Bushehr

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Bushehr University of Medical Sciences
Full name of responsible person
Dr. Afshin Ostovar
Street address
Research Center، Bushehr University of Medical Sciences , Sabzabad
City
Bushehr
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Bushehr University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Bushehr University of Medical Sciences
Full name of responsible person
DR. Shahnaz Pouladi
Position
Nursing Ph.D.
Other areas of specialty/work
Street address
Bushehr-Bushehr University of Medical Sciences-College of Nursing and Midwifery
City
Bushehr
Postal code
Phone
+98 77 3345 0178
Fax
Email
Pouladi2008@yahoo.comSh.Pooladi@bpums.ac.ir
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Bushehr University of Medical Sciences
Full name of responsible person
DR . Shahnaz Pouladi
Position
Nursing Ph.D.
Other areas of specialty/work
Street address
Bushehr University of Medical Sciences
City
Bushehr
Postal code
Phone
+98 77 3345 0178
Fax
Email
Pouladi2008@yahoo.comSh.Pooladi@bpums.ac.ir
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Bushehr University of Medical Sciences
Full name of responsible person
Dr. Shahnaz Pouladi
Position
Nursing Ph.D
Other areas of specialty/work
Street address
Bushehr University of Medical Sciences-college of Nursing and Midwifery
City
Bushehr
Postal code
Phone
+98 77 3345 0178
Fax
Email
Pouladi2008@yahoo.comSh.Pooladi@bpums.ac.ir
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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