The aim of this study is to investigate the efficacy of sublingual misoprostol to reduce blood loss in cesarean delivery. In this randomized control trail, 90 pregnant women who are at risk of post partum hemorrhage will be divided into two groups, first group will receive sublingual misoprostol (400 microgram) and oxytocin and the control group will receive oxytocin. Hemoglobin and need for additional uterotonic during operation will be compared between groups.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2016041125648N3
Registration date:2016-04-26, 1395/02/07
Registration timing:registered_while_recruiting
Last update:
Update count:0
Registration date
2016-04-26, 1395/02/07
Registrant information
Name
Masoumeh Mirteimori
Name of organization / entity
Mashhad University of Medical Sciemces
Country
Iran (Islamic Republic of)
Phone
+98 915 113 0199
Email address
rahmanish3@mums.ac.ir
Recruitment status
Recruitment complete
Funding source
Mashhad University of Medical Sciences
Expected recruitment start date
2016-03-30, 1395/01/11
Expected recruitment end date
2016-05-01, 1395/02/12
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Sublingual Misoprostol to Reduce Blood Loss in Cesarean Delivery
Public title
Sublingual Misoprostol to Reduce Blood Loss in Cesarean Delivery
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria are: any of post partum hemorrhage risk factors in term pregnancies like uterine over distention (macrosomia or multiple pregnancies); arrested descent labor; prolonged induction.
Exclusion criteria are: coagulopathies; anemia; adhesion bands,; organ damage during surgery (intestine; colon; Bladder; etc); allergy for prostaglandins, abnormal placenta; need for extended surgery incision and underlying diseases (diabetes mellitus; hypertension; ischemic heart disease; etc).
Age
No age limit
Gender
Female
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
90
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics committee of Mashhad University of Medical Sciences
Street address
Qoreishi Building, Daneshgah Street, Mashhad University of Medical Sciences, Mashhad, Iran Mashhad