Protocol summary

Summary
The aim of this study is to evaluate the therapeutic effects of shock wave on the spasticity of lower limbs in patients with cerebral stroke. In this single blind clinical trial (Another clinician who was not aware of the patients categorization performed the measurements), 28 cerebral stroke patients from both genders will enter the study according to the inclusion and exclusion criteria. The patients will be divided in to two groups of intervention and control (each 14). The intervention group will receive one shock wave session a week for three weeks. The shock wave focus probe will be placed on the medial and lateral head junction of Gastrocnemius and 1500 shocks with 4 HZ in frequency and 0.1 mJ/Cm2 in intensity will be administered. Calves muscles stretching exercise will also be performed. The control group will only receive stretching exercises. The patients spasticity grade will be evaluated according to Modified Ashworth scale. The pain scale will be evaluated by VAS score. The Lower extremity functional index questionnaire will be used for evaluating the lower limb function. The clonus degree and ankle range of motion also will be checked. The time required for six meter walking will be assessed using by TUG test. All the mentioned tests in both groups will be evaluated at the base line, 1th, 3d, 12th week and compared between groups.

General information

Acronym
IRCT registration information
IRCT registration number: IRCT2016010225803N1
Registration date: 2016-08-05, 1395/05/15
Registration timing: retrospective

Last update:
Update count: 0
Registration date
2016-08-05, 1395/05/15
Registrant information
Name
Maryam Mellat Ardekani
Name of organization / entity
MD, Resident of Physical medicine and rehabilitation
Country
Iran (Islamic Republic of)
Phone
+98 31 3227 1332
Email address
maryammellat@resident.mui.ac.ir
Recruitment status
Recruitment complete
Funding source
Financial resources of the Isfahan University of Medical Science
Expected recruitment start date
2015-03-20, 1393/12/29
Expected recruitment end date
2016-01-19, 1394/10/29
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The effect of EXtracorporal shock wave therapy on plantar spasticity fallowing cerbral stroke: A randomized controlled trial
Public title
The effect of shock wave therapy on spasticity of post stroke
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria( age between 18-80; at least one month after CVA; concept of information consent; spasticity score in Modified Ashworth scale in 2-4 Exclusion criteria: (liver failure; pregnancy; History of malignancy; ankle contracture; severe inflammation in treated region; history of Botulinum injection in Gastrocnemius muscle in the past 6 months or phenol and alcohol; unwillingness to continue participating in the study.
Age
From 18 years old to 80 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size: 28
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Single blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Isfahan University of Medical Science
Street address
Isfahan University of Medical Science, Hezar jirib Avenue
City
Isfahan
Postal code
Approval date
2014-11-26, 1393/09/05
Ethics committee reference number
394191

Health conditions studied

1

Description of health condition studied
stroke
ICD-10 code
I64
ICD-10 code description
Stroke, not specified as haemorrhage or infarction

2

Description of health condition studied
spasm
ICD-10 code
R25.2
ICD-10 code description
Cramp and Spasm

Primary outcomes

1

Description
Modified Ashworth scale
Timepoint
Base line, 1, 3, 12 weeks after begining of intervention in control and intervention groups.
Method of measurement
By examiner

2

Description
Clonus measurment
Timepoint
Base line, 1, 3, 12 weeks after begining of intervention in control and intervention groups.
Method of measurement
Examiner

3

Description
Time Up and Go test
Timepoint
Base line, 1, 3, 12 weeks after begining of intervention in control and intervention groups.
Method of measurement
Chronometer

4

Description
Ankle range of motion
Timepoint
Base line, 1, 3, 12 weeks after begining of intervention in control and intervention groups.
Method of measurement
Goniometer

5

Description
Pain
Timepoint
Base line, 1, 3, 12 weeks after begining of intervention in control and intervention groups.
Method of measurement
VAS

6

Description
Lower limb function
Timepoint
Base line, 1, 3, 12 weeks after begining of intervention in control and intervention groups.
Method of measurement
Lower limb functional scale questionaire

Secondary outcomes

empty

Intervention groups

1

Description
The Intervention group will receive one shock wave session a week for three weeks. The shock wave focus probe will be placed on the medial and lateral head junction of Gastrocnemius and 1500 shocks with 4HZ intensity and 0.1 mJ/CM2 will be administered. Calves muscle stertching exercises will also be performed.
Category
Rehabilitation

2

Description
In Control group, only Gastrocnemius muscles stretching exercise will be done in home.
Category
Rehabilitation

Recruitment centers

1

Recruitment center
Name of recruitment center
kashani Hospital
Full name of responsible person
DR. Maryam Mellat Ardakani, Resident of Physical medicine and rehabilitation
Street address
Kashani Hospital, Kashani Avenue, Isfahan, Isfahan
City
Isfahan

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Vice chancellor for research of Isfahan University of Medical Siences
Full name of responsible person
Dr. Mansour Siavash
Street address
Vice chancellor for research, Isfahan University of Medical Sciences, Hezar Jerib Avenue, Isfahan
City
Isfahan
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice chancellor for research of Isfahan University of Medical Siences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Isfahan University of Medical Science
Full name of responsible person
Maryam Mellat Ardekani
Position
MD Resident of Physical medecine and rehabilitation
Other areas of specialty/work
Street address
Physical medicine and rehabilitation department, Azahra hospital, Soffeh Avenue
City
Isfahan
Postal code
Phone
00
Fax
Email
maryammellat2000@yahoo.com
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Isfahan University of Medical Science
Full name of responsible person
Maryam Mellat Ardakani
Position
MD Resident of Physical medecine and rehabilitation
Other areas of specialty/work
Street address
physical medecine and rehabilitation department, Azahra hospital, Soffeh Avenue
City
Isfahan
Postal code
Phone
+98 31 3227 1332
Fax
Email
maryammellat2000@yahoo.com
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Isfahan University of Medical Science
Full name of responsible person
Maryam Mellat Ardekani
Position
MD Resident of Physical medicine and rehabilitation
Other areas of specialty/work
Street address
City
Physical medicine and rehabilitation department, Azahra hospital, Soffeh Avenue
Postal code
Phone
00
Fax
Email
maryammellat2000@yahoo.com
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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