Protocol summary

Summary
In this study, the effects of clove jell in the treatment for premature ejaculation are compared to placebo.This study is a double-blind, placebo-control, phase II randomized clinical trial with a sample size of 50 patients. All of the subjects with intravaginal ejaculation latency time less than 1 minutes would be enrolled in the study after considering the general state of health and rule out of erectile dysfunction. After random allocation, subjects divided into two groups and each group received clove jell 1% or placebo. Participants take the drugs for 2 months. All of them record IELT (Intravaginal ejaculation latency time) with a stopwatch four weeks before the intervention and during it . Mean of IELT in the three last intercourse before and during intervention will be compared. The PEDT (premature ejaculation diagnostic tool) questionnaire will be completed for each participant at the beginning and end of the study.

General information

Acronym
IRCT registration information
IRCT registration number: IRCT2016013126298N1
Registration date: 2016-02-13, 1394/11/24
Registration timing: prospective

Last update:
Update count: 0
Registration date
2016-02-13, 1394/11/24
Registrant information
Name
Ahmad Reza Sharifi Olounabadi
Name of organization / entity
Baqiatallah University of Medical Science, Department of Traditional Iranian Medicine
Country
Iran (Islamic Republic of)
Phone
+98 21 8804 0060
Email address
a-sharifi@shahed.ac.ir
Recruitment status
Recruitment complete
Funding source
Vice chancellor for research, Shahed University of Medical Sciences
Expected recruitment start date
2016-02-14, 1394/11/25
Expected recruitment end date
2016-07-20, 1395/04/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Assessment of effect of clove jell in the treatment for premature ejaculation
Public title
effect of clove in premature ejaculation
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria:monogamous and heterosexual 18-40 years old man; Intravaginal ejaculation latency time less than 1 minutes; PEDT (Premature ejaculation diagnostic tool) questionnaire score more than eight Exclusion criteria: History of severe or debilitating disease; diabetes; cardiac disease; liver disease; mental disease; thyroid dysfunction; addiction to any drugs or substances; pregnancy of wife; history of hypersensitivity to clove
Age
From 18 years old to 40 years old
Gender
Male
Phase
2
Groups that have been masked
No information
Sample size
Target sample size: 50
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Used
Assignment
Parallel
Other design features
random allocation: table of random digits

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics Committee of Shahed University of Medical Science
Street address
In front of the Holy Shrine of Imam Khomeini, khalij-e-Fars (Tehran-Qom) Highway
City
Tehran
Postal code
3319118651
Approval date
2016-01-25, 1394/11/05
Ethics committee reference number
shahed.REC.1394.55

Health conditions studied

1

Description of health condition studied
premature ejaculation
ICD-10 code
F52.4
ICD-10 code description
Premature ejaculation

Primary outcomes

1

Description
ejaculation latency time
Timepoint
4 weeks before intervention and 2 months during it, 10 minutes before intercourse
Method of measurement
stopwatch

Secondary outcomes

1

Description
Premature ejaculation diagnostic tool questionnaire score
Timepoint
Before and after study
Method of measurement
Questionnaire

Intervention groups

1

Description
clove oil 1%, 10 minutes before intercourse, for 2 months prepared in Shahid Beheshti University of Medical Science, School of Pharmacy
Category
Treatment - Drugs

2

Description
placebo jell
Category
Placebo

Recruitment centers

1

Recruitment center
Name of recruitment center
Family Health Clinic of Shahed University
Full name of responsible person
Ahmad Reza Sharifi Olounabadi
Street address
Italy Ave., Palestine Sq.
City
Tehran

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Vice chancellor for research, Shahed University of Medical Sciences
Full name of responsible person
Dr. Mohsen Naseri
Street address
Traditional Medicine Clinical Trial Research Center; No.1471; Between Forsat and Nosrat Ave; North Kargar Ave; Enghelab Sq.
City
Tehran
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice chancellor for research, Shahed University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Shahed University of Medical Sciences
Full name of responsible person
Dr. Ahmad Reza Sharifi Olounabadi
Position
Resident PhD of Iranian Traditional Medicine
Other areas of specialty/work
Street address
Center of TIM Health Care؛ Third Dashtestan Ave؛ Shariati Ave.
City
Tehran
Postal code
Phone
+98 21 2288 2596
Fax
Email
a-sharifi@shahed.ac.ir sharifiahmaddr@gmail.com
Web page address

Person responsible for scientific inquiries

Contact
Name of organization / entity
Shahed University of Medical Sciences, Mostfa Khomeini Hospital
Full name of responsible person
Dr. Fereidun Khayyamfar
Position
Urologist
Other areas of specialty/work
Street address
Italy Aven., Palestine Sq.
City
Tehran
Postal code
Phone
+98 21 8898 5918
Fax
Email
KHAYYAMFAR@YAHOO.COM
Web page address

Person responsible for updating data

Contact
Name of organization / entity
Shahed University
Full name of responsible person
Dr. Ahmad Reza Sharifi Olounabadi
Position
Resident of Ph.D Iranian Traditional Medicine
Other areas of specialty/work
Street address
Third Dashtestan Ave؛ Shariati Ave؛ Tehran.
City
Tehran
Postal code
Phone
00
Fax
Email
Web page address

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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