Main goal: evaluation the efficacy of Ubiquinon on Angiogenic growth factors in patients with Gastric cancer. Inclusion criteria: age between 25 to 75 years old; healthy function of liver and kidney; gastric cancer diagnosis. Exclusion criteria: chemotherapy; food supplement or other dietary regimen; diabetes mellitus. Patients with gastric cancer who referred to Shafa hospital under supervision of oncologist will be recruited in this study. Sample size in each group will be 30. All of them before chemotherapy are divided in two groups and then under the supervision of dietitian will be under supplementation with 200 mg Coenzyme Q10. 5 cc blood from all participant will obtain and blood keep in -30 C until analysis, for analyzing following parameters: CEA, CA 19-9, CA125
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2016120826390N8
Registration date:2016-12-13, 1395/09/23
Registration timing:prospective
Last update:
Update count:0
Registration date
2016-12-13, 1395/09/23
Registrant information
Name
Ehsan Ghaedi
Name of organization / entity
Ahwaz Jundishapoor ,University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 61 3374 3285
Email address
ghaedi.e@ajums.ac.ir
Recruitment status
Recruitment complete
Funding source
Ahwaz Jundishapour University of Medical Sciences
Expected recruitment start date
2017-03-21, 1396/01/01
Expected recruitment end date
2018-03-21, 1397/01/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Evaluation the efficacy of Ubiquinon on Tumor markers in patients with Gastric cancer
Public title
Effect of ubiquinon on Gastric cancer
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: age between 25 to 75 years old; healthy function of liver and kidney; gastric cancer diagnosis. Exclusion criteria: chemotherapy; food supplement or other dietary regimen; diabetes mellitus.
Age
From 25 years old to 75 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
60
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ahwaz Jondishapoor Uneversity of Medical Sciences
Street address
Ahwaz, Golestan Blvd, AJUMS
City
Ahwaz
Postal code
Approval date
2016-07-19, 1395/04/29
Ethics committee reference number
IR.AJUMS.REC.1395.486
Health conditions studied
1
Description of health condition studied
Gastric cancer
ICD-10 code
C16
ICD-10 code description
Malignant neoplasm of stomach
Primary outcomes
1
Description
Carcinoembryonic Antigen
Timepoint
Before and after study
Method of measurement
Laboratory kits
2
Description
Carbohydraate Antigen 19-9
Timepoint
Before and after study
Method of measurement
Laboratory kits
3
Description
Carbohydraate Antigen 125
Timepoint
Before and after study
Method of measurement
Laboratory kits
Secondary outcomes
1
Description
weight
Timepoint
Befor and after Study
Method of measurement
Sensitive Balance
Intervention groups
1
Description
Patients will experience CoenzymeQ10 200 mg supplementation under supervision of dietition for 3 month intervention group
Category
Treatment - Drugs
2
Description
Patients in control group will take placebo in the same number as intervention group for 3 month.