study aims: Regarding to avoid of compromising the immune system after exhaustive exercise and the role of micronutrients in this background, the aim of this study was to investigate the effect of vitamin C supplementation on the salivary immunoglobulin A, cortisol and total protein concentration on active girls college following exhaustive physical activity program.
Inclusion Key criteria was that must participants be athlete and not suffering the common cold,exclusion Key criteria have been that subjects be
involving common cold, The study population girl students of Lorestan University of Physical Education and the sample size were in the first of the twenty-four that participated voluntarily Then, was reduced to seventeen sample size because of loss of participants during performances and randomly assigned into three groups: exercise - vitamin C supplementation (n=6), exercise (n=5) and control group (n = 6). exercise - vitamin C supplementation group perform study physical activity program for7 days in AM and PM, with receive 500 mg vitamin C tablets in a fasting term daily, exercise groups performed same protocol without supplementation receive, and the control group performed neither the physical activity nor received the supplement. Saliva samples were collected one day before starting the physical activity program and also 24 and 72 hours after the last session, in 9/30 morning then The factors immunoglobulin A, cortisol and salivary total protein were measured that are as the primary outcome variable of the study.