According to the study method, 24 endurance runners were randomly selected from male athletes in Khorramabad city and randomly divided into three groups: taurine-activity, placebo-activity and control. Taurine groups consumption will supplement Taurine 15 mg per kilogram of body weight on daily and the placebo groups consumption will in the same amount of wheat germ and group both will perform three times the exercise protocol in the week, while the control group did not receive any supplement and follow its normal schedule. Blood samples from subjects will be collectedin in three stages (48 hours before the start of the period, before executing the exercise protocol and immediately after the end of the period) in 5 cc of the anterior vein of the forearm in sitting position. Then after collection, samples are transferred to the laboratory for examination. At first, the samples are centrifuged at 3000 rpm to separate the serum and serum samples are then analyzed using Eliza Kit's product from Boosters USA company by immunosorbent method attached to the sandwich enzyme to measure glutathione peroxidase, superoxide dismutase, malondialdehyde.
General information
Acronym
GPX
IRCT registration information
IRCT registration number:IRCT2017052128429N3
Registration date:2017-07-25, 1396/05/03
Registration timing:retrospective
Last update:
Update count:0
Registration date
2017-07-25, 1396/05/03
Registrant information
Name
Mohammd Fathi
Name of organization / entity
Lorestan University
Country
Iran (Islamic Republic of)
Phone
+98 916 397 2041
Email address
fathi.m@lu.ac.ir
Recruitment status
Recruitment complete
Funding source
Investigator
Expected recruitment start date
2017-04-17, 1396/01/28
Expected recruitment end date
2017-05-18, 1396/02/28
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparison of the effect of Taurine supplementation on liver antioxidant levels during a period of endurance activity in endurance athletes
Public title
Effect of Taurine Supplementation on Levels of Liver Antioxidants.
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria: Subjects the lack of particular diseases, especially liver and heart disease - respiratory.
Exclusion criteria: People with specific diseases, especially heart disease and liver - respiratory.
Age
No age limit
Gender
Male
Phase
2-3
Groups that have been masked
No information
Sample size
Target sample size:
24
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics Committee of Lorestan University of Medical Sciences.
Street address
Department of Physical Education and Sport Sciences, University of Lorestan, 5 km road Tehran, Khorramabad, Lorestan
City
Khoramabad
Postal code
Approval date
2016-09-22, 1395/07/01
Ethics committee reference number
5476
Health conditions studied
1
Description of health condition studied
ICD-10 code
ICD-10 code description
Primary outcomes
1
Description
Enzymes Superoxide dismutase
Timepoint
Two days before , The day begining of and on the last day of the intervention
Method of measurement
In a sandwich enzyme-linked immunosorbent assay
Secondary outcomes
1
Description
No variable
Timepoint
not measurement
Method of measurement
not sampling
Intervention groups
1
Description
The control group does twelve sessions of activity without receiving supplements and placebo
Category
Prevention
2
Description
The intervention group does training sessions twelve with the receive of Taurine supplementation
Category
Treatment - Drugs
3
Description
The placebo group does training sessions twelve with placebo receive.
Category
Placebo
Recruitment centers
1
Recruitment center
Name of recruitment center
Lorestan University
Full name of responsible person
Mohammad Fathi
Street address
Department of Physical Education and Sport Sciences, University of Lorestan, 5 km road Tehran, Khorramabad, Lorestan
City
Khormabad
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Investigator
Full name of responsible person
Mohamad Fathi
Street address
Department of Physical Education and Sport Sciences, University of Lorestan, 5 km road Tehran, Khorramabad, Lorestan
City
Khoramabad
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Investigator
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Lorestan University
Full name of responsible person
Mohammad Fathi
Position
Assistant Professor Lorestan University
Other areas of specialty/work
Street address
Department of Physical Education and Sport Sciences, University of Lorestan, 5 km road Tehran, Khorramabad, Lorestan
City
Khoramabad
Postal code
Phone
00
Fax
+98 938 920 5366
Email
javidfathi@gmail.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Lorestan University
Full name of responsible person
Mohamad Fathi
Position
Assistant professor and faculty at the University of Lorestan
Other areas of specialty/work
Street address
Department of Physical Education and Sport Sciences, University of Lorestan, 5 km road Tehran, Khorramabad, Lorestan
City
Khoramabad
Postal code
Phone
00
Fax
+98 938 920 5366
Email
javidfathi@gmail.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Lorestan University
Full name of responsible person
Mohamad Fathi
Position
Assistant professor and faculty at the University of Lorestan
Other areas of specialty/work
Street address
Department of Physical Education and Sport Sciences, University of Lorestan, 5 km road Tehran, Khorramabad, Lorestan
City
Khoramabad
Postal code
Phone
00
Fax
Email
javidfathi@gmail.com
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)