This study after clinical trials confirm the Shahid rajaei Heart Hospital Ethics Committee and head of the relevant sections of satisfaction. two parts simple and random ICUB and ICUA for sampling patients group and intervention( A) group are specified control( B). Using the results of a similar article (2013Maryam Mirzaie) sample size per group of 51 people. Open heart surgery is 110 people nominated to enter according to the inclusion criteria can be included and of all written consent. clinic a few days before patients by basic business information and anesthesiologist and demographic them in the form before registration. All patients in the operating room of a protocol will be entitled to the same anesthesia. For all patients to cpb connection time, duration, duration of anesthesia, aorta clamps the duration of the action in the action during the registration form. In the control group (ICUB) from the beginning of the entry of patients into the next section of the action are attached to the surface until the ventilator , according to the previous hospital routine, based on the criterion of the hemodynamic parameters and Glasgowcoma index to be measured and recorded by mental nurse. sedation level in the intervention group with the use of the CIS Any two spectral index measured for some themes and can be recorded. In both groups of medicinal drugs contain almost the same protocol to the PCA pump, persedex, Midazolam, morphine, ketrolac, apotel . For both groups in postoperative chart the amount of incoming mechanical ventilation, duration of sedating, duration of ICU stay duration of hospital admission record. then the data were analyzed by SPSS 22 case analysis.