Protocol summary

Summary
This study is designed to compare two treatment modalities of the ankle sprain. This is a single center, double-blind randomized trial. One hundred and twenty patients of 18 to 60 years with grade 1 and 2 ankle sprains are enrolled, who are visited at the emergency department within 48 hours after the injury. Patients who have fractures or other injuries, or those who cannot be followed are excluded from the study. After the initial evaluation, patients are randomly divided into two groups. They pick up one of the envelopes in which two types of treatments are written. They are unaware of envelopes contents. Then, they enroll to the treatment groups of A (short leg cast) or B (short leg splint). Patients will be evaluated two and six weeks after the treatment regarding pain score, rate of swelling, and range of motion of the joint. The researcher is also unaware of the type of therapy. Treatment is done by another emergency physician and researcher only evaluates the variables and outcomes.

General information

Acronym
IRCT registration information
IRCT registration number: IRCT2016071528941N1
Registration date: 2017-01-30, 1395/11/11
Registration timing: retrospective

Last update:
Update count: 0
Registration date
2017-01-30, 1395/11/11
Registrant information
Name
Homa Javan
Name of organization / entity
Mashhad University of Medical Sciencess
Country
Iran (Islamic Republic of)
Phone
+98 51 3841 1538
Email address
javanh931@mums.ac.ir
Recruitment status
Recruitment complete
Funding source
Vice chancellor for research, Mashhad University of Medical Sciences
Expected recruitment start date
2016-07-31, 1395/05/10
Expected recruitment end date
2016-10-21, 1395/07/30
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Comparing the efficacy of casting and splinting in the treatment of ligament injuries of ankle sprain
Public title
Difference between casting and splinting in the treatment of ankle sprain
Purpose
Treatment
Inclusion/Exclusion criteria
Inclusion criteria: Patients of 18 to 60 years old who are visited over the past 48 hours due to ankle sprain. Exclusion criteria: Patients with fractures, multiple injuries, debilitating disease, grade 3 ligament injury or patients who are from another city or not consent to the study.
Age
From 18 years old to 60 years old
Gender
Both
Phase
3
Groups that have been masked
No information
Sample size
Target sample size: 120
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features

Secondary Ids

empty

Ethics committees

1

Ethics committee
Name of ethics committee
Ethics committee of Mashhad University of Medical Sciences
Street address
Next to the Hoveize cinema, Daneshgah Street
City
Mashhad
Postal code
91388-13944
Approval date
2016-01-20, 1394/10/30
Ethics committee reference number
ir.mums.fm.rec.1394.533

Health conditions studied

1

Description of health condition studied
Ankle sprain
ICD-10 code
S93.4
ICD-10 code description
Calcaneofibular (ligament); Deltoid (ligament); Internal collateral (ligament); Talofibular (ligament); Tibiofibular (ligament), distal

Primary outcomes

1

Description
Pain score
Timepoint
Before the intervention, two and six weeks after the intervention
Method of measurement
Visual Analogue Scale

2

Description
Ability to walking
Timepoint
Before the intervention, two and six weeks after the intervention
Method of measurement
Questionnaire

3

Description
Range of motion of ankle joint
Timepoint
Before the intervention, two and six weeks after the intervention
Method of measurement
Questionnaire

Secondary outcomes

1

Description
Pain score
Timepoint
Before the intervention, two and six weeks after the intervention
Method of measurement
Visual Analogue Scale

2

Description
Ability to walking
Timepoint
Before the intervention, two and six weeks after the intervention
Method of measurement
Questionnaire

3

Description
Range of motion of ankle joint
Timepoint
Before the intervention, two and six weeks after the intervention
Method of measurement
Questionnaire

Intervention groups

1

Description
Intervention group: In this group, full immobilization of ankle is done using the short leg cast. First, one layer of wibril is wrapped around the patient's leg (from the lower part of the knee to the metatarsophalangeal joint). Then, the plaster of paris (gipsoband) is soaked in water. Then, it is wrapped in several layers around the wibril and molded. The leg is protected until drying and hardening of the plaster.
Category
Treatment - Other

2

Description
Control Group: In this group, ankle is immobilized using short leg splint. A pre-prepared packs of splint is placed at the posterior part of the patient's foot (from the lower part of the knee to the metatarsophalangeal joint), after soaking in water. Then, it is rounded and closed with an elastic band.
Category
Treatment - Other

Recruitment centers

1

Recruitment center
Name of recruitment center
Edalatian Emergency Department, Imam Reza Hospital
Full name of responsible person
Homa Javan
Street address
Imam Reza Square, Ibnesina Avenue
City
Mashhad

Sponsors / Funding sources

1

Sponsor
Name of organization / entity
Vice chancellor for research, Mashhad University of Medical Sciences
Full name of responsible person
Mohsen Tafaghodi
Street address
Next to the Hoveize cinema, Daneshgah Street
City
Mashhad
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice chancellor for research, Mashhad University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty

Person responsible for general inquiries

Contact
Name of organization / entity
Mashhad University of Medical Sciences
Full name of responsible person
Homa Javan
Position
Resident of Emergency Medicine, MD
Other areas of specialty/work
Street address
Next to the Hoveize cinema, Daneshgah Street
City
Mashhad
Postal code
Phone
+98 51 3854 3031
Fax
Email
Javanh931@mums.ac.ir; HOMA_JAVAN@YAHOO.COM
Web page address
www.mums.ac.ir

Person responsible for scientific inquiries

Contact
Name of organization / entity
Mashhad University of Medical Sciences
Full name of responsible person
Ehsan Bolvardi
Position
Assistant professor of Emergency Medicine
Other areas of specialty/work
Street address
Next to the Hoveize cinema, Daneshgah Street
City
Mashhad
Postal code
Phone
+98 51 3854 3031
Fax
Email
bolvardie@mums.ac.ir
Web page address
www.mums.ac.ir

Person responsible for updating data

Contact
Name of organization / entity
Mashhad University of Medical Sciences
Full name of responsible person
Homa Javan
Position
Resident of Emergency Medicine
Other areas of specialty/work
Street address
Next to the Hoveize cinema, Daneshgah Street
City
Mashhad
Postal code
Phone
+98 51 3854 3031
Fax
Email
Javanh931@mums.ac.ir
Web page address
www.mums.ac.ir

Sharing plan

Deidentified Individual Participant Data Set (IPD)
empty
Study Protocol
empty
Statistical Analysis Plan
empty
Informed Consent Form
empty
Clinical Study Report
empty
Analytic Code
empty
Data Dictionary
empty
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