The aim of this study is to evaluate the Anti-caries effect of two common mouthwashes in the market. In this experimental study, 30 Dental students will be selected. Voluntaries will be divided into two groups containing 15 peoples. Saliva samples will be taken from each group. Each group will use the mouthwash for 2 weeks, twice a day, 15 cc for each time, and they will have consume mouthrinses for 30 seconds.
Inclusion criteria: not to use antibiotics within past 3 months; DMFT:5-7; not to use xylitol gum; not to use topical fluoride treatments in the last 4 weekes; not to wear orthodontic appliances.
Exclusion criteria: not to use the mouthwashes(according to researcher prescription)
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2016073129133N1
Registration date:2016-09-05, 1395/06/15
Registration timing:retrospective
Last update:
Update count:0
Registration date
2016-09-05, 1395/06/15
Registrant information
Name
Neda Gholami
Name of organization / entity
Zanjan University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 21 7770 1401
Email address
dr.gholami.n@zums.ac.ir
Recruitment status
Recruitment complete
Funding source
Vice chancellor for research, Zanjan University of Medical Sciences
Expected recruitment start date
2016-04-20, 1395/02/01
Expected recruitment end date
2016-05-21, 1395/03/01
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
The comparison of chlorhexidine 0.2% and combination of xylitol and fluoride 920 ppm mouthwashs on salivary Streptococcus mutans count (in vivo)
Public title
The comparison of chlorhexidine and fichs Mouthwashs on salivary Cariogenic bacterias in dental students of Zanjan university of medical sciences
Purpose
Prevention
Inclusion/Exclusion criteria
Inclusion criteria: not to use antibiotics within past 3 months; DMFT:5-7; not to use xylitol gum; not to use topical fluoride treatments in the last 4 weekes; not to wear orthodontic appliances.
Exclusion criteria: not to use the mouthwashes(according to researcher prescription)
Age
No age limit
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
30
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
in this study block randomization was used to randomize the groups
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics committee of Zanjan University of Medical Sciences
Street address
Azadi Square, Zanjan, Zanjan University of Medical Sciences
City
Zanjan
Postal code
13191-45156
Approval date
2016-03-03, 1394/12/13
Ethics committee reference number
zums.rec.1394.291
Health conditions studied
1
Description of health condition studied
Dental caries
ICD-10 code
K02
ICD-10 code description
Dental caries
Primary outcomes
1
Description
The amount of Streptococcus mutans in saliva
Timepoint
2 weeks
Method of measurement
Counting colonies in the laboratory
Secondary outcomes
1
Description
-
Timepoint
-
Method of measurement
-
Intervention groups
1
Description
Intervention group:using Fuchs mouthwashe produced by Fuchs(Germany),containing Xylitol and Fluride 920ppm for 2 weeks,twice a day;30 seconds each time
Category
Treatment - Drugs
2
Description
Control group: using Chlorhexidine 0.2% produced by Najo(Iran) for 2 weeks,twice a day;30 seconds each time
Category
Treatment - Drugs
Recruitment centers
1
Recruitment center
Name of recruitment center
Faculty of dentistry, Zanjan University of Medical Sciences
Full name of responsible person
Dr Elham Zajkani
Street address
Azadi Square, Zanjan, Zanjan University of Medical Sciences
City
Zanjan
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Vice Chancellor for research of Zanjan University of Medical Sciences
Full name of responsible person
dr Masud Vakili
Street address
Azadi Square, Zanjan, Zanjan University of Medical Sciences
City
Zanjan
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Vice Chancellor for research of Zanjan University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Zanjan University of Medical Sciences
Full name of responsible person
Dr Elham Zajkani
Position
Assistant Professor , School of Dentistry Department of restorative Dentistry
Other areas of specialty/work
Street address
Azadi Square, Zanjan, Zanjan University of Medical Sciences
City
Zanjan
Postal code
Phone
+98 24 3342 4766
Fax
Email
elham.zajkanident@gmail.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Zanjan University of Medical Sciences
Full name of responsible person
Dr Elham Zajkani
Position
Assistant Professor of restorative dentistry
Other areas of specialty/work
Street address
Azadi Square, Zanjan, Zanjan University of Medical Sciences
City
Zanjan
Postal code
Phone
+98 24 3342 4766
Fax
Email
elham.zajkanident@gmail.com
Web page address
Person responsible for updating data
Contact
Sharing plan
Deidentified Individual Participant Data Set (IPD)