Comparison of the effect of anti-osteoporosis therapies on the repair of osteoporotic fractures in patientss admitted to the orthopedic ward

Determination of the effect of anti-osteoporosis drugs on osteoporotic fractures repair in hospitalized patients

In this research, 75 eligible patients referring to Imam Khomeini Hospital of sari suffering from osteoporotic fracture were chosen purposefully and were randomly divided into three groups of control and intervention one and two by Table of random numbers.

This study was conducted at Imam Khomeini Hospital and among patients who entered the study according to inclusion criteria. Then, patients will be divided into three groups according to the random numbers table. The first group, after the surgery, received 1200 mg daily calcium, vitamin D 800 units and alendoronitis ; 70 mg / week for 3 months before being discharged from the hospital. The second group will be treated with calcium and vitamin D and the injectable parathyroid hormone branded synapar ;0.08 cc daily in the abdomen for 3 months. The third group of patients from patients admitted to the service of other orthopedic professors who receive only 1200 milligrams of calcium daily and vitamin D 800 units. Then they will be followed up after the discharge. After 1 month and 3 months, patients will be followed up by telephone over their medications and their acceptance capacity, as well as the side effects of drugs and the incidence of fracture. Patients will also be requested at week 4 and 8 and 12, and after surgery to check the amount of restoration of fracture by radiography. Also, in follow-up 3 months later, bone density measurement will be done at the same center by the same technician. . And if the patient situation does not improve, the patient's will continue the treatment according to bone Densimetry.

major inclusin and exclusion criteria: Patients Aged over 50 years, with a sudden fracture of the wrist, vertebra or hip with Tscore less than 2.5 - who have undergone a Corrective surgical procedure, and Do not take anti-osteoporosis drugs including bisphosphonate, calcitonin, raloxifene, and parathyroid hormone over the past 6 months before fracture were included; Patients who have Previous history of osteoporotic fractures, Multiple trauma, Cancer, Other diseases requiring aggressive, corticosteroid, or immunosuppressive therapy and Selective arthroplasty were excluded

Intervention group one: 1200 mg daily calcium, vitamin D-800 units plus parathyroid hormone injections branded sinopar Intervention group two: daily 1200 mg calcium, vitamin D 800 units plus alendoronitis made with a dose of 70 mg Control group: daily calcium group 1200 mg, vitamin D 800 units

The rate of fracture restoration

Random by using Random NumbersTable