After drying the leaves of origanum vulgare extracted with 80% methanol by maceration method. And formulation of a mouthwash is prepared. All patients in the study first visit (treated with scaling and root planing and polished) were within 3 weeks to continue his habit oral hygiene procedures. Clinical measurements will be done within 3 weeks, and the clinical characteristics of plaque, gingivitis and bleeding gums and staining recorded At this point, all patients receiving mouthwash is said that each group corresponding to your mouth (1. Mouthwashes marjoram, 2. chlorhexidine rinses, 3 placebo) for 3 weeks are arranged along a toothbrush hitting use (15 ml mouthwash for 30 seconds and 2 times per day). After three weeks, patients were recalled and re-measure and record factors that cause periodontal finally, the data will be analyzed by statistical software.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2016120531242N1
Registration date:2017-03-13, 1395/12/23
Registration timing:registered_while_recruiting
Last update:
Update count:0
Registration date
2017-03-13, 1395/12/23
Registrant information
Name
Emran Habibi
Name of organization / entity
Mazandaran University of Medical sciences
Country
Iran (Islamic Republic of)
Phone
+98 11 3354 3761
Email address
ehabibi@mazums.ac.ir
Recruitment status
Recruitment complete
Funding source
Deputy of Research and Technology, Mazandaran University of Medical Sciences
Expected recruitment start date
2017-03-05, 1395/12/15
Expected recruitment end date
2017-07-06, 1396/04/15
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Clinical effect of Oregano mouth wash on periodontal indexes compare with chlorhexidine
Public title
Clinical effect of Oregano mouth wash
Purpose
Treatment
Inclusion/Exclusion criteria
Having 12 incisors; mild to moderate gingivitis and absence of pocket and loss of attachment; absence of color in the tooth and the lack of allergy to chlorhexidine and Origanum vulgare; non-use of intraoral removable prosthesis; history of antibiotic use 3 last month and no smoking.
Age
From 20 years old to 50 years old
Gender
Both
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
60
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Double blinded
Blinding description
Placebo
Used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Mazandaran University of Medical Sceinces
Street address
Moalem Ave.
City
sari
Postal code
Approval date
2016-02-01, 1394/11/12
Ethics committee reference number
IR.MAZUMS.REC.94-1823
Health conditions studied
1
Description of health condition studied
Gingivitis
ICD-10 code
K05
ICD-10 code description
Gingivitis and periodontal diseases
Primary outcomes
1
Description
The clinical characteristics of plaque
Timepoint
before and after treatment
Method of measurement
Observation
2
Description
Gingival inflammation
Timepoint
before and after treatment
Method of measurement
Observation
3
Description
Gingival bleeding
Timepoint
before and after treatment
Method of measurement
Observation
4
Description
Staining of teeth
Timepoint
before and after treatment
Method of measurement
Observation
Secondary outcomes
1
Description
Oral allergy
Timepoint
During the study, and then
Method of measurement
observation
Intervention groups
1
Description
15 ml Marjoram mouthwash 2 times a day for 3 weeks
Category
Treatment - Drugs
2
Description
15 ml Chlorhexidine 2 times a day for 3 weeks
Category
Treatment - Drugs
3
Description
15 ml placebo mouthwash two times a day for 3 weeks
Category
Placebo
Recruitment centers
1
Recruitment center
Name of recruitment center
Specialized Private Dental clinic
Full name of responsible person
Mahmoud Khosravi
Street address
City
Sari
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Mazandaran University of Medical Sciences
Full name of responsible person
Ahmad Ali Enayati
Street address
Mazandaran University of Medical Sciences, Moalen Avenue
City
Sari
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Mazandaran University of Medical Sciences
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Mazandaran University of Medical Sciences
Full name of responsible person
Emran Habibi
Position
Ph.D. Assistant Professor
Other areas of specialty/work
Street address
School of Pharmacy, Farah Abad
City
Sari
Postal code
Phone
+98 11 3354 3761
Fax
Email
emrapharm@yahoo.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Sari School of Pharmacy
Full name of responsible person
Emran Habibi
Position
Ph.D
Other areas of specialty/work
Street address
School of Pharmacy, Farah Abad
City
Sari
Postal code
Phone
+98 11 3354 3761
Fax
Email
emrapharm@yahoo.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Mazandaran University of Medical Sciences
Full name of responsible person
Emran Habibi
Position
Ph.D Assistant Professor
Other areas of specialty/work
Street address
School of Pharmacy, Farah Abad
City
Sari
Postal code
Phone
+98 11 3354 3761
Fax
Email
Web page address
Sharing plan
Deidentified Individual Participant Data Set (IPD)