desmopressin effects on bleeding after functional endoscopic sinus surgery on patients with chronic rhinosinusitis with and without polyposis

Determination of the effect of desmopressin on the reduction of bleeding during surgery in FESS surgeries

The blocking method will be used to select patients in one of the two intervention and control arms so that they are selected using the random numbers table of the 4 blocks and then the items will be selected and introduced with time review. It should be noted that in this study, the patients, the team of surgeons, the anesthetic team and the operating room team did not know the control or intervention of the patients.

In the operating room of Amiralam Hospital, 100 ml of normal saline was injected to both groups half an hour before surgery. In the control group, it contained only normal saline and in the intervention group containing 0.1 μgr / kg desmopressin. In this study Patients, the team of surgeons, the anesthetic team and the operating room team are unaware of the control or intervention of the patients, and the intervention group and the placebo group are both surgically treated by a professor

Patients with chronic Rhinosinusitis in the age group of 15-60 years without heart disease and underlying coagulation disorders, without high blood pressure

In both groups, 100 ml of normal serum saline was injected half an hour before surgery. In the control group, this serum only contained normal saline and in the intervention group containing 0.1 μgr / kg desmopressin. After surgery, if the surgery field is not satisfied by the surgeon, the 100th second serum is prescribed in both groups, and after half an hour if bleeding is repeated, 100 cc is also prescribed.

Reduction of bleeding during surgery, surgeon satisfaction from the field of operation and shortening the duration of the FESS surgery.

Patients eligible for inclusion in the study are interviewed first and explained to the project, and, if satisfied, to participate in the study, the patients will receive written consent to be included in the plan and informed of them. They will be randomly assigned to either group. The blocking method will be used to select patients in one of the two intervention and control arms so that they are selected using the random numbers table of the 4 blocks and then the items will be selected and introduced with time review. It should be noted that in this study, the patients, the team of surgeons, the anesthetic team and the operating room team did not know the control or intervention of the patients, and the intervention group and the placebo group were both surgically operated by a professor, and for both groups 100 cc My head is ready to be used, which the surgical team and the data analyst do not know about its nature.

In this study, the patients, the team of surgeons, the anesthetic team and the operating room team were unaware of the control or intervention of the patients, and the intervention group and the placebo group were both surgically treated by a professor.

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