The effect of local magnesium sulfate on the progression of effacement, dilatation, process and delivery outcomes in nulipar women

1. Determine and compare the amount of effacement and dilatation of the cervix in the magnesium sulfate group and control before intervention. 2. Determining and comparing the amount of effacement and dilatation of cervix in magnesium sulfate group and control after intervention 3. Determination and comparison of cesarean delivery in magnesium sulfate and control group 4 Determine and compare the degree of rupture of grade 3 and 4 in magnesium sulfate and control group 5. Determination and comparison of postpartum hemoglobin and hematocrit changes in magnesium sulfate and control group 6 Determine and compare the duration of labor in the magnesium sulfate and control group 7. Determine and compare apgar score 1 and 5 neonates in magnesium sulfate and control group

In this study, 72 nulipar pregnant women who are referred to the Mahdieh hospital for admission to delivery and have incloud criteri to the study are examined. Contributors will be placed in control or intervention groups according to the randomized random numbers table. Treatment groups are identified by codes A and B, and each participant is assigned a code.

This is a triple blind clinical trial performed at Shahid Beheshti University of Medical Sciences in Mahdieh Hospital. The method of blindness, drug use or placebo is performed by the researcher and follow-up is done by the research fellow. Fellow researchers and patients are unaware of the treatment group. After the completion of the data, the data is analyzed by the spss software, the analyst is also unaware of the treatment groups

Incloud criteria; nuliparous, gestational age 37-42 weeks, age 18-35 years, single and live fetus, cefalic presntation; Conditions of failure to enter: having chronic, risky illness CPD disorder Estimated baby weight more than 4000 grams or less than 2500 grams High risk pregnancy Having history of infertility

After giving explanations to the samples, they are informed consent. In the active phase, 10 cc magnesium sulfate 50% will be deposited on the uterine cervix and in the control group 10 cc of distilled water will be used, and then the delivery process and its consequences including delivery type, newborn Apgar score and rate Blood and laceration in the delivery canal be measured and compared in both the control and intervention groups.

The type of delivery, the amount of bleeding, the length of delivery and the Apgar score

Deputy of Research of Shahid Beheshti Nursing Faculty

Randomization was done using random numbers tabel . For the control and intervention group, codes A and B were used as contractions. Then, before the intervention, using Excel software, a randomized table for the order of sampling was prepared.

Before starting the intervention, all the specimens needed explanations, but the samples were not known to be in the intervention or control group. The drug or placebo was prescribed by the investigator, but the assistant in the study who performed the examinations with him from the treatment group was unaware. The attending physician was aware of the patient's treatment group, but the person analyzing the statistical information from the treatment group was unaware.

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