The Aim of this Study is to Investigate the Effect of of 12 Weeks of Water Aerobic Exercise and Atorvastain drug on ANP and BNP in older Men With Cardiovascular disesaes.Inclusion Criteria: Cardiovascular Patients With At least 30% Stenosis And a History Of Hospital Admission Have to be Considered Criteria Were Selected. Exclusion Criteria: Not respecting the Recommendations of the Study, the Researchers, Causing Serious Illness or lack of Desire to Continue Research Will be Considered. In this study, We chose 40 patients with cardiovascular Disease that Will be Divideded in to four groups. Experimental groups Shall be Select exercise 3 times per weeks during 3 months with the method of walking on the Water and Carnal Swimming. The Results Will expressed as the mean ± sd, and all Statistical comparisons were made by means of a one-way ANOVA test, followed by Tukey’sPost-Hoc analysis. We Will conclud that the Effect of Exercise and Intervention taking Atorvastatin to Reduction ANP and BNP Followed by the reduction of Disease cardio - vascular and improve cardiovascular function.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT2017060633030N2
Registration date:2017-06-15, 1396/03/25
Registration timing:registered_while_recruiting
Last update:
Update count:0
Registration date
2017-06-15, 1396/03/25
Registrant information
Name
Mohsen Davoodi
Name of organization / entity
Medical Science Of Shiraz University
Country
Iran (Islamic Republic of)
Phone
+98 71 3212 2313
Email address
mdavoodi827@gmail.com
Recruitment status
Recruitment complete
Funding source
Investigator
Expected recruitment start date
2017-06-10, 1396/03/20
Expected recruitment end date
2017-07-11, 1396/04/20
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Clinical Trials Of Comparative Effect Exercise And Atorvastatin Drug Upon Natriuretic Peptides In Cardiovascular Patients
Public title
Intervention of Exercise and Atorvastatin Drug On Heart Natriuretic peptides.
Purpose
Other
Inclusion/Exclusion criteria
Inclusion Criteria; Cardiovascular Patients With At least 30% Stenosis And a History Of Hospital Admission Have to be Considered Criteria Were Selected.
Exclusion Criteria; Not respecting the Recommendations of the Study, the Researchers, Causing Serious Illness or lack of Desire to Continue Research Will be Considered.
Age
From 50 years old to 65 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
40
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Single
Other design features
Will be Select At Random and Targeted Sampling Method and Randomly Shall be Divided in to Four Groups
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Ethics Committee of Shiraz University of Medical Sciences
Street address
ZAND Boulvard; Central Department of Medical Science of Shiraz; State 5 ;Mohsen Davoodi; Radiology Department
City
Shiraz
Postal code
7134814336
Approval date
2017-01-06, 1395/10/17
Ethics committee reference number
11917-95
Health conditions studied
1
Description of health condition studied
CHD
ICD-10 code
125.2
ICD-10 code description
Chronic ischaemic heart disease
Primary outcomes
1
Description
Brain Natriuretic Peptides
Timepoint
Pre Intervention and 12 Weeks Post Intervention
Method of measurement
Pg/ML With ELISA Method
2
Description
Atrum Natriuretic Peptides
Timepoint
Pre Intervention and 12 Weeks Post Intervention
Method of measurement
Pg/ML With ELISA Method
Secondary outcomes
empty
Intervention groups
1
Description
Intervention Group: Atorvastatin Drog,Hydroxy methyl Glutarat , 14 Hours Half Life,
20 Mg- One Dose Per Day,
For 12 Weeks,After dinner will be eaten, LOGHMANDrug Company
Category
Treatment - Drugs
2
Description
Intervention Exercise Group:
Aerobic Exercise Including Walking on the water and Carnal swiming, For 12 Weeks,Three Sessions of Exercise per Week, 50 to 65 % Intensity VO2 Max,Controled with Polar Heart Rate
Category
Rehabilitation
3
Description
Intervention Group,Exercise and Atorvastatin:Aerobic Exercise Including Walking on the water and Carnal swiming, For 12 Weeks,Three Sessions of Exercise per Week, 50 to 65 % Intensity VO2 Max,Controled with Polar Heart Rate;
Atorvastatin Drog,Hydroxy methyl Glutarat , 14 Hours Half Life,
20 Mg- One Dose Per Day,
For 12 Weeks,After dinner will be eaten, LOGHMANDrug Company;
Category
Treatment - Other
4
Description
Control Group: Without Exercise and Without Taking medication.
Category
N/A
Recruitment centers
1
Recruitment center
Name of recruitment center
Medical Science Of Shiraz, Namazi Hospital
Full name of responsible person
Mohsen Akbari
Street address
References Laberatory, Namazi Hospital of Shiraz
City
Shiraz
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Medical Science of Shiraz
Full name of responsible person
Dr,Mohsen Davoodi
Street address
Zand Boulevard; 5 State In Medical Science University of Shiraz; Radiology Group
City
Shiraz
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Medical Science of Shiraz
Proportion provided by this source
100
Public or private sector
empty
Domestic or foreign origin
empty
Category of foreign source of funding
empty
Country of origin
Type of organization providing the funding
empty
Person responsible for general inquiries
Contact
Name of organization / entity
Medical Science of Shiraz
Full name of responsible person
Dr,Mohsendavoodi
Position
Manager of Department of Fars Radiology
Other areas of specialty/work
Street address
Zand Boulevard, Medical Science of Shiraz, Radiology Department
City
Shiraz
Postal code
Phone
+98 71 3212 2313
Fax
Email
mdavoodi827@gmail.com
Web page address
Person responsible for scientific inquiries
Contact
Name of organization / entity
Medical Science of Shiraz,Shiraz; Iran
Full name of responsible person
Dr,Mohsen davoodi
Position
PHD of Cardio vascular Sport Physiology
Other areas of specialty/work
Street address
Zand Boulevard , Medical Science of Shiraz, Department of Radiology
City
Shiraz
Postal code
Phone
+98 71 3212 2313
Fax
Email
mdavoodi827@gmail.com
Web page address
Person responsible for updating data
Contact
Name of organization / entity
Medical Science of shiraz
Full name of responsible person
Dr,Mohsen Davoodi
Position
PHD of Cardiovascular Sport Physiology
Other areas of specialty/work
Street address
Zand Boulevard,Medical Science University of Shiraz, Radiology Department
City
shiraz
Postal code
Phone
+98 71 3212 2313
Fax
Email
mdavoodi827@gmail.com
Web page address
MohsenDavoodi.blogfa.com
Sharing plan
Deidentified Individual Participant Data Set (IPD)