The present study was designed to see the effect of moderate and high intensity resistant training on the inflammatory markers and cardiovascular risk factors in non-athlete students.For this purpose 30 healthy students (20 to 26 years old) with no previous record of any chronic diseases or using any specific drugs who did not do any regular exercises in the past two years were selected. 24 hours before starting the experiment a sample of venous blood was collected from each individual. Subjects were divided randomly into three equal groups (N=10). First two groups underwent moderate and severe resistance exercises training for six consecutive weeks. The third group was considered as control group. At the end of the study a sample of venous blood was collected from all subjects and was analyzed for inflammatory and other cardiovascular risk factors including HDL,LDL ApoA, ApoB, Cholesterol, Triglyceride, LPL and fibrinogen. systolic and diastolic blood pressures and body mass index before and after intervention were measured and compared.
General information
Acronym
IRCT registration information
IRCT registration number:IRCT138809042770N1
Registration date:2010-10-12, 1389/07/20
Registration timing:retrospective
Last update:
Update count:0
Registration date
2010-10-12, 1389/07/20
Registrant information
Name
Slahadin Ahmadi
Name of organization / entity
Kurdistan University of Medical Sciences
Country
Iran (Islamic Republic of)
Phone
+98 87 1613 1399
Email address
slahadin@muk.ac.ir
Recruitment status
Recruitment complete
Funding source
kurdistan University of Medical Sciences & Kurdistan University
Expected recruitment start date
2008-01-30, 1386/11/10
Expected recruitment end date
2009-01-30, 1387/11/11
Actual recruitment start date
empty
Actual recruitment end date
empty
Trial completion date
empty
Scientific title
Effect of moderate and high resistant training on the inflammatory markers and cardiovascular risk factors in non-athlete students
Public title
Effect of moderate and high resistant training on the inflammatory markers and cardiovascular risk factors in non-athlete students
Purpose
Health service research
Inclusion/Exclusion criteria
Inclusion Criteria: Healthy young students with no previous record of any specific drug use and routine regular exercises during the last two years.
Exclusion: Unhealthy, Doing regular exercise during the last two years.
Age
From 20 years old to 26 years old
Gender
Male
Phase
N/A
Groups that have been masked
No information
Sample size
Target sample size:
30
Randomization (investigator's opinion)
Randomized
Randomization description
Blinding (investigator's opinion)
Not blinded
Blinding description
Placebo
Not used
Assignment
Parallel
Other design features
Secondary Ids
empty
Ethics committees
1
Ethics committee
Name of ethics committee
Kurdistan University of Medical Sciences
Street address
vice chancellor for research, Kurdistan University of Medical Sciences
City
sanandaj
Postal code
6617713446
Approval date
2009-03-17, 1387/12/27
Ethics committee reference number
پ/14/پ12093
Health conditions studied
1
Description of health condition studied
cardiovascular risk factor and inflammatory markers
by collecting venous blood and measuring serum levels of related variables before and at the end of the study.
2
Description
Lipoprotein Lipase
Timepoint
6 weeks
Method of measurement
by collecting venous blood before and at the end of study and measuring serum levels using LPL kit
3
Description
Interleukin1 and Interleukin 6
Timepoint
6 weeks
Method of measurement
by collecting venous blood before and at the end of study and measuring serum levels of related factors using Enzyme-linked immunosorbent assay (ELISA)
4
Description
hs-CRP (high-sensitivity CRP) and fibrinogen
Timepoint
6 weeks
Method of measurement
by collecting venous blood before and at the end of study and measuring serum levels using related kits
5
Description
Body Mass Index
Timepoint
6 weeks
Method of measurement
bybody composition analyzer (Biospase CO, Ltd)
6
Description
Waist Hip Ratio
Timepoint
6 weeks
Method of measurement
By measuring Hip and Waist circumferences by measuring tape
7
Description
Systolic and diastolic Blood pressure
Timepoint
6 weeks
Method of measurement
sphygmomanometer
Secondary outcomes
empty
Intervention groups
1
Description
Subjects in high intensitiy resistance group undergwent exercise regime consist of three sessions of resistance training per week for six consecutive weeks. In each session they did three sets of 4-6 repetitions at intensity of 80-90% of 1-RM (one repetition maximum).
Category
Other
2
Description
Subjects in moderate intensitiy resistance group undergwent exercise regime consist of three sessions of resistance training per week for six consecutive weeks. In each session they did three sets of 10-12 repetitions at intensity of 45-55% of 1-RM (one repetition maximum).
Category
Other
3
Description
Subjects of the control group did not do any regular physical activities during the period of study.
Category
Other
Recruitment centers
1
Recruitment center
Name of recruitment center
Kurdistan university
Full name of responsible person
Slahadin Ahmadi
Street address
Pasdaran street
City
Sanandaj
Sponsors / Funding sources
1
Sponsor
Name of organization / entity
Kurdistan University of Medical Sciences, vice chancellor for research
Full name of responsible person
Ataollah Haidari
Street address
Kurdistan University of Medical Sciences
City
Sanandaj
Grant name
Grant code / Reference number
Is the source of funding the same sponsor organization/entity?
Yes
Title of funding source
Kurdistan University of Medical Sciences, vice chancellor for research